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About Medford mail tribune. (Medford, Or.) 1909-1989 | View Entire Issue (Nov. 7, 1958)
14 MAIL TRIBUNE, Mcdfortf, Ortjon, ttMiy, November 7, ItSi Speeding of Body Chemistry During Healing Studied I ' 6 t k"' iff Deloi Smith Br DELOS SMITH X7PI Science Editor New York -UPJ- The pos sibility of science learning how to shift the gears (so to mfcTn"-" speak) in the i body chemis- i.f tJp"A try of an in jured person in order to speed the healing of his wound shas been raised by experi ments with the "growth' chemical of cows in the bodies of white rats. This chemical, a "hormone," Is in abundance in the in fancy and youth of all animals and people. It keeps the per tinent body chemistry geared to the business of providing chemical building blocks with out which the tissues and or gans could not expand in growth. When full growth is accomDlished, the hormoD goes into short supply and the high gear is disengaged. Presumably these building blocks are urgently needed by wounds and the more the chemistry provides, the faster they heal. So Dr. John F Prudden, Gentaro Nishihara, and Lourdes Ocampo of Co lumbia University's College of Physicians and Surgeons put it to the test. Seven-Day Interval They took 168 rats which were almost identical as to strain, age, and weight. One half of them were injected daily with cows' growth hor mone and this was believed to have made them young again in stepped - up supplies of building blocks. A long surgical wound was made along the belly of each rat. Seven days were allowed for the healing process to take its course, and then all the wounds were tested to de termine the tensile strength of the new tissue which was knitting the two sides of the cuts together. The tensile strength in the wounds of all the treated rats was greater than that in the wounds of the paired "con trols." On the average it was 8.8 per cent greater which showed these . wounds were healing that much faster. This the scientists took as a clear' demonstration that they had shifted rat Chemistry over to speedy tissue-building. Large Doses Dangerous At this stage, the experi ment can't be tried in people because cow growth hormone seems to be inactive in them. However, Prudden and his as sociates, in reporting to the American College of Sur geons, said they had reason to believe that it would be ac tive if larger doses were in jected into them. Larger doses could mean peril, and they said they were still engaged in preliminary studies. The chemistry involved Is that of nutrition. It has two sides. One tears down your food into its very basic chemi cals, amino acids and such. The other side takes those basic chemicals, or "building blocks," and makes new cells and tissues with them. Growth hormone is one of the many body - regulating chemicals manufactured by the pituitary gland. 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