14 MAIL TRIBUNE, Mcdfortf, Ortjon, ttMiy, November 7, ItSi
Speeding of Body
Chemistry During
Healing Studied
I ' 6 t k"' iff
Deloi Smith
Br DELOS SMITH
X7PI Science Editor
New York -UPJ- The pos
sibility of science learning
how to shift the gears (so to
mfcTn"-" speak) in the
i body chemis-
i.f tJp"A try of an in
jured person
in order to
speed the
healing of his
wound shas
been raised
by experi
ments with
the "growth'
chemical of cows in the bodies
of white rats.
This chemical, a "hormone,"
Is in abundance in the in
fancy and youth of all animals
and people. It keeps the per
tinent body chemistry geared
to the business of providing
chemical building blocks with
out which the tissues and or
gans could not expand in
growth. When full growth is
accomDlished, the hormoD
goes into short supply and the
high gear is disengaged.
Presumably these building
blocks are urgently needed by
wounds and the more the
chemistry provides, the faster
they heal. So Dr. John F
Prudden, Gentaro Nishihara,
and Lourdes Ocampo of Co
lumbia University's College of
Physicians and Surgeons put
it to the test.
Seven-Day Interval
They took 168 rats which
were almost identical as to
strain, age, and weight. One
half of them were injected
daily with cows' growth hor
mone and this was believed to
have made them young again
in stepped - up supplies of
building blocks.
A long surgical wound was
made along the belly of each
rat. Seven days were allowed
for the healing process to take
its course, and then all the
wounds were tested to de
termine the tensile strength of
the new tissue which was
knitting the two sides of the
cuts together.
The tensile strength in the
wounds of all the treated rats
was greater than that in the
wounds of the paired "con
trols." On the average it was
8.8 per cent greater which
showed these . wounds were
healing that much faster. This
the scientists took as a clear'
demonstration that they had
shifted rat Chemistry over to
speedy tissue-building.
Large Doses Dangerous
At this stage, the experi
ment can't be tried in people
because cow growth hormone
seems to be inactive in them.
However, Prudden and his as
sociates, in reporting to the
American College of Sur
geons, said they had reason to
believe that it would be ac
tive if larger doses were in
jected into them. Larger doses
could mean peril, and they
said they were still engaged
in preliminary studies.
The chemistry involved Is
that of nutrition. It has two
sides. One tears down your
food into its very basic chemi
cals, amino acids and such.
The other side takes those
basic chemicals, or "building
blocks," and makes new cells
and tissues with them.
Growth hormone is one of
the many body - regulating
chemicals manufactured by
the pituitary gland.
Tax Changes To Be
Discussed by CPAs
Tax changes in 1958 af
fecting small business will be
discussed at a meeting of the
Salem, Eugene and Southern
Oregon chapters of the Ore
gon Society of Certified Pub
lic Accountants at- the Uni
versity of Oregon in Eugene
Saturday.
Glenn F. Schneider, CPA
president of the southern Ore
gon chapter, said special em
phasis will be given to the
much-discussed election which
must be made by Dec. 1 of a
corporation not to be taxed
as a corporation.
Salem - (UPD - Oregon small
forest owners met here Thurs
day to discuss better use of
small stands of private timber.
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