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About Oregon daily emerald. (Eugene, Or.) 1920-2012 | View Entire Issue (Oct. 30, 2000)
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With your vote, RALPH can win! For more information, contact Lane Victory 2000. (541) 681-9774 or (541) 607-8093 228 E. 11th (between High and Pearl in Eugene) Paid for by Lane Victory 2000 and not authorized by any candidate or candidate’s committee. Tom Patterson Emerald University Assistant Professor of chemistry Andrew Marcus has created a new way to examine a cell’s behavior using a laser array and quickly pulsing light, named Fourier Imaging Correlation Spectroscopy. Cellular science progresses ■ A UO Professor of chemistry has developed a new, faster technique to study the molecular behavior of cells By Brooke Ross Oregon Daily Emerald University Assistant Professor of chemistry Andrew Marcus has cre ated a new technique using light to study cellular materials in an effort to learn more about the structure and dynamics of molecular move ment within cells. Marcus is using the technique, which he named Fourier Imaging Correlation Spectroscopy, to study mitochondria, which are responsi ble for movement within the cell membrane. Mitochondria are im portant to study because they have a lot of metabolic processes and can give knowledge about certain diseases such as diabetes.“We now have a faster way to study a cell’s behavior, which should help push scientific technology further,” Marcus said. The process involves illuminat ing a cell with a pattern of light millions of times per second, and studying the noise created by mo lecular motion, he said. This noise helps Marcus interpret cellular be havior. Marcus’ work took three years to complete and is funded by the University, the National Science Foundation and the American Heart Association. Marcus said there are several ad vantages to using the FICS tech nique. One benefit is that it allows for the observation of molecular systems within better time resolu tions. It is now possible to study proteins, which make up how all living things work, in microsecond time scales, he said. “A lot of biological action hap pens in this time scale,” Marcus said. FICS also allows scientists to study cells for longer periods of time without killing them, he said. The finding is especially impor tant to the medical field because using the system makes it easier to distinguish healthy cells from self destructing cells, he said, adding that this knowledge will give phar maceutical companies and the health industry added information about diseases. Graduate student Michelle Knowles is also involved in the FICS research. Knowles, who has been involved with the work for over a year, works in Marcus’ lab and prepares cell slides and ob serves their movements. “I hope to see this work carried out, so we can learn more about mitochondrial diseases in the fu ture,” she said. After developing FICS, Marcus joined with University professor Roderick Capaldi, an expert on mi tochondria, to study the motion of mitochondria. Marcus said the two professors have been able to learn from each other’s areas of expertise. Several graduate students are currently involved in the ongoing research, including Daciana Mar gineando, who studies the struc ture of the cell’s membrane in Ca paldi’s lab. “We’ve done the underground work, but now we want to address the biological questions,” she said. Margineando works with a more traditional imaging technique called digital video fluorescence microscopy, which allows her to see the structures and observe the position of the mitochondria. By using both techniques, the re searchers are able understand not only what the mitochondria look like, but what they are doing. She hopes to see the research be come more thorough so it will be possible to study the inside of oth er cell elements in order to under stand the dynamics of cellular structures. Oregon Daily Emerald P.O. Box 3159, Eugene OR 97403 The Oregon Daily Emerald is published daily Monday through Friday during the school year and Tuesday and Thursday during the summer by the Oregon Daily Emerald Publishing Co. Inc., at the Uni versity of Oregon, Eugene, Oregon. A member of the Associated Press, the Emerald operates independently of the University with offices in Suite 300 of the Erb Memorial Union. The Emerald is pri vate property. The unlawful removal or use of papers is prosecutable by law. NEWSROOM — (541)346-5511 Editor in chief. Jack Clifford Managing editor: Jessica Blanchard Community: Darren Freeman, editor. Lindsay Buchele, Rebecca Newell, reporters. Freelance: Serena Markstrom, editor. Higher education: Andrew Adams, editor. Kristy Hessman, Brooke Ross, reporters. 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