Image provided by: University of Oregon Libraries; Eugene, OR
About Medford mail tribune. (Medford, Or.) 1909-1989 | View Entire Issue (Aug. 10, 1962)
MLUrUrtU MAIL IHiauwt;, MfcDrOKO. OREGON Thalidomide Experience Reveals Need Editor'! not.: TM. I. ik lilt of three dispatcher on i h Thalidomide tragedy. It ipelli out exiiling gov ernment rules for regula . ting new drug product! end explains new legisla tive proposals being advo cated for protection of the public. By RONALD H. NESSEN Washington (UPD Ameri ca's narrow escape from the tragic consequences of Thali domide on newborn infants paradoxically shows both the effectiveness of current drug laws and the need for tight er restrictions. Existing regulations, en forced with dogged determin ation by Dr. Frances O. Kel ey of the Food and Drug Ad ministration, blocked the sale in this country of the German developed sedative which has been blamed for the birth de formaties of children in Ger many, England and Canada. But there were no rules to prevent the American manu facturer, W. S. Merrell Co., of Cincinnati, from sending "thalidomide to 1,231 doctors lor testing on human patients. There is no rule requiring that patients be advised when they are given an ex perimental drug. There is no rule requiring that the government be notified in ad vance when a manufacturer distributes medicine for so called "clinical testing" on human beings. Procedures Considered President Kennedy told his news conference last week the government was considering how to tighten administrative procedures to make the test ing of new drugs on humans less dangerous. Kennedy also urged Con gress to approve this year the legislation he proposed to toughen safeguards against dangerous and useless drugs. The bill is needed, he said, "to prevent even more serious disasters" in the future. No drug may be sold in the United States unless it is ap proved by the Food and POCKET MONEY... can make for a trunkful of good times this summer. Wherever your vacation takes you, take enough money. One-visit service. IQCAL IDAN 535 E. JACKSON BLVD. MtdforrJ Shoppinc Ctntir rhone: 773-7456 Dick Webb, Mir. Opto FrUiy Evanfrifs 'Til 7 With Trade $17.43 Month JOHNSTON STORES Drug Administration. About three in every 10 drugs submitted to the FDA are rejected. It takes the agen cy an average of 62 days to approve a new drug. How ever, .-nany cases stretch out for six months or more and in some instances the process takes two or three years. Tested on Animals Beiore applying to the FDA, a manufacturer tests a new drug on several species of animals. If no ill effects show up, the next step is to try out the compound on hu mans. This is done by sending the drug to a selected list of doc tors who agree to give it to their patients and report back the results. Kennedy, FDA officials and others feel this is one of the most dangerous points in the drug testing process. Among the new administra tive moves under considera tion by the FDA to make this step safer is stricter policing of doctors supplied with ex perimental drugs to make sure they have adequate test facilities and submit meaning ful reports to the manufactur er. ei i III i iiliJ. ', i.iaTit-gliir .'.i-ta-Jri WALKS OUT - John Albert Kerr, 46, whose death sen tence was commuted by Cali fornia Gov. Earl Warren in 1953, is shown as he walked out of San Quentin Prison, subject to parole supervision for life. Kerr was convicted of first degree murder in the slaying of Troy R. Buckles, Fresno grocer, in 1950. Kerr will not be permitted to re turn to Fresno. (UPD Soon To Be At The j Jwi'i'i I VsS j j Allo"e ( Also said to be under study are new regulations to re quire drug makers to notify the FDA when they start test ing a new medicine and to in form the agency immediately if any injurious side effects turn up during tests. Under current procedures, a drug manufacturer comes to the FDA only after tests on animals and humans are complete and the firm is seek ing approval to market the product. Permission Asked In September. 1960, the Merrell Co applied to the FDA for permission to mar ket Thalidomide, a drug wide ly used in Germany and else where abroad as a sleeping pill which left no hangover and was free of the danger of overdose. The application was handed over to Dr. Kelsey, a Cana dian - born pharmacologist and physician. It was her first assignment upon joining the FDA. In the face of what she re calls as Merrell's "very anx ious" desire to win approval. Dr. Kelsey was not convinced by the data the company sub mitted claiming Thalidomide was completely safe. When the 60-day period aft er which the firm automatic ally could have marketed the drug expired, she ordered .an extension. She did this again and again with the backing of her superiors. In February, 1961, Dr. Kel sey chanced to read in the British Medical Journal a report suggesting that use of Thalidomide over a long per iod might lead to a condition marked by numbness and itch ing in the hands and feet. This was the first hint that the drug might have toxic effects. Then, Merrell was notified from Europe late last Novem STAR. By CLAY yp MAR. 3! jSS-APIt. 20 . JK, Your Dotty Activity Guide L , "l According to he Stars. To develop message for Saturday, t read words corresponding to numbers X of your Zodioc birth sign. rT 6-55 66 731 rd74-76-77 jf TAURUS APR. 21 I MAY 21 S 2 Your TWork 31 Support 32 Faces. 33 3e 34 Just 3 5 Take 36Show 37See 4 38 Expenses 39 New I0 Thinking 41 Or -12 For 43 And 44 Cautious 45Tho la Listen 47 Result 48 How 49 And ' 3 Change ' i Keep 5 You 6Do 8 New 9F,r)ur lOFriends 1 1 Wart I 12 Best 13 Personal 14Atoi 1 5 Awhile 1 6 Closely , 17 Friendship 1 8 Seenet 19Good 20Goin 21 Smrlrng 22 Peace 23 To 24 Crwm 25W.II 26 And 27 On 28 And 29 Your r 7-19-30-41 51-62-72 GEMINI MAY 22 & -A JUNE 22 W 1-U2S-36 t-' 47-58-6? CANCER jkjj JULY 23 S 3-18-29-401 M-61-7t 7985 uo 50 S t JULY2 r J AUG. 23 53 54 55 56 57 58 59 60 I 8-17-28-3S1 50-60-81-861 VIRGO AUG. 24 SEPT. 2? 30 New il2-!3-34-46 57-68-88-901 0g)Gooil t) Adverse Refrigerator Medford Shopping Center ber that Thalidomide given to mothers in the early months of pregnancy was suspected of causing phocomelia - a heretofore rare malady in which babies are born with flipper - like arms, missing limbs and other deformities. Application Withdrawn On Nov. 30, 1961, Merrell notified the FDA of this re port and withdrew its applica tion for approval to sell the drug in the United States. At the same time, the com pany contacted the doctors testing Thalidomide on hu mans and warned them not to give it to women of child bearing age. Motivation Authority Joins Medical Staff Portland - Dr. Judson S. Brown, nationally recognized authority on motivation, has been appointed professor of medical psychology at the University of Oregon Medical school, according to an an nouncement by Dr. D. W. E. Baird, dean. Dr. Brown, formerly gradu ate research professor in the psychology department at the University of Florida, receiv ed his master's degree from the University of California and his doctorate from Yale university. Before joining the Universi ty of Florida staff he was on the faculty of both Harvard and Yale universities and the State University of Iowa. Dr. Brown, author of the book, "The Motivation of Be havior," is a Fellow of the American Psychological asso ciation, an honorary life mem ber of the Midwestern Psy chological association and a charter member of the Psy chonomic society. GAXElC) R. POIXAN LIBRA EPT.23 4-22-33-445 154-65-80-83VB1 5CORPIO 61 Pattern 62 In 63 And 64 Surround 65 Money 66 To 67 Today 68 Let 69 Daydream 70 Be 71 Witt 73A.M 73 Buiid 74 Up 75 You 7oYour ri Health OCT. 24 ', NOV. 22 52-63-82-84 SAGITTARIUS N0V.23 A. OEC 22 r.-Si 9-16-27-38 49-70-78 CAPRICORN UK.. 23 AJv JAN. 20 VTj$ 9.T.94.1;S 78 Economical 79Delinlle!y 145-56-67 V Prosperity BU 15 Conversation 8 1 Ara AQUARIUS Moves 82 Progressive Gaiety Where SomcrnlnJ Limelight Today Don't The Opening! 83 Involved 84 Plans 8b Benefit 86 Indicated 87 Tide 88 Other 89Turns 90TOI1; DNcuuil 10-21-32-43O 15364-75 Vy. fisces MAR. 21 -1fi 11-15-26-3741 48-59-87-89Va RCA WHIRLPOOL Automatic Defrost With Freezer Below 112 SOUTH RIVERSIDE fi In March, Merrell told the doctors to stop using the drug entirely and destroy or re turn any remaining supplies. By then it was clear that Thalidomide had caused thousands of babies to be born deformed in Germany, Eng- Rate Hearings For Truck Freight To Be Continued Salem -0IPIU Another phase of the hearings to raise truck freight rates in the state 10 per cent has closed. Salem hearings on the re quest of the Pacific Inland Tariff Bureau wound up Wed nesday. Hearings, which have been going on all this month, resume in Portland Aug. IS. The proposed rate increase would include all truck freight shipments In the state. The increase is sought to offset higher labor costs brought about by a recent contract. It would replace a tempo rary additional per shipment charge now in effect pending the outcome of the present hearings before a Public Util ity Commission examiner. PUC officials said that if the requested rate increase is granted it would boost truck rates above the present tem porary level. Most of the witnesses who have appeared before Hear ing Examiner Malcolm Jones so far have been represental tives of the trucking firms who have favored the in creases. . . Opponents are expected to be heard at the coming Portland session. In addition to the 10 per cent rate hike the industry also is seeking to increase shipments of 20,000 or more pounds three cents per hun dred and increase the pres ent $2.50 minimum shipping charge to $3. Oregon Highway Group Sells Timber Salem-IUPD-The State High way commission Thursday sold for $386,000 timber on land that it bought for less than $3,000 in the 1930s. The timber is located on three of five tracts bought for right-of-way and forest way sides on the Carpenterville Brookings section of the old Coast highway. The high offer in competi tive bidding came from Brookings Plywood Co. No of fers were made on the other two tracts. The commission will keep the land. TOTAL CAPACITY 13.8 cu. ft. FREEZER HOLDS 163 lbs. 32" wide 65" high FHIDAY. AUGUST 10, 1962 J for Tighter Drug Regulations land and other foreign coun tries. The new drug legislation Kennedy wants congress to approve would give the gov ernment control over manu facturing standards of medi cine makers. The firms also would have to prove to the FDA that new drugs are ef fective as well as safe. To accomplish this, the bill would require new drug ap plicants to open to govern ment inspectors all records on the safety and effectiveness of a medicine. Drug names would be stan dardized, the government would be given new authority to police the sale of barbitu rates and stimulant drugs and a federal safety stamp would be required on cosmetics. Could Order Withdrawal The government would be able to order a drug with drawn from sale if dangerous side effects showed up after the FDA had given its ap proval. At present, the gov ernment must seek a court order to halt the marketing of an approved drug. ) J CLOSE OUT SWIM CAPS WHILE STOCKS LAST SORRY-WE FORGOT ABOUT XMAS CARDS IN OUR XMAS SALE SO HERE THEY GO - 2 FOR THE PRICE OF 1 PACKING SUPPLIES As in the past Western Thrift has a complete line of quality packers sup plies at the lowest prices. A FEW OF THE MANY ITEMS BEING FEATURED IN OUR COSMETIC DEPARTMENT AT VERY SPECIAL PRICES COUNTESS MARITZA Summer Colognes O fin 5 POPULAR FRAGRANCES A $2.50 VALUE FOR Tussy's Pink Cleansing Cream PLUS SKIN LOTION OR S")00 SKIN FRESHNER $3.00 VALUE BOTH a WiiBlr Take your youngsters to the "2 O's" your doctor and dentist before sending them back to the "3 R's." When your children pass pre school "health exams" they find it easier to pass their school exams, because good health goes hand-in-hand with steady attendance and good study habits. Make appointments with your doctor and dentist today they can help your children avoid going through "School Daze." Add Federal Excite Tax T I 'tltLV.'.Vi J MEDFORD'S ORIGINAL DISCOUNT STORE The House Commerce Com mittee has held four days of hearings on the measure. A committee source says more hearings are planned but no date has been set. The out look for the bill is not good. The Senate Judiciary Com mittee has written its own drug bill which Kennedy says is too weak. In criticizing this bill, Ken nedy pointed to the complaints of Sen. E s t e s Kefauver (D-Tenn.), whose subcommit tee conducted lengthy hear ings on the drug industry. Kefauver says the commit THE BIBLE SPEAKS TO YOU Sunday, 9:00 a.m. K-SHA-860kc Thii uttk't Chrittian Science irof "God, Mm and Heaven In th Spaca Agt" Sea Siren or Crest FORMERLY 85c ea. 2,85 tMf lat. 11 on Taxable Merchandise tee bill, a toned down version of his own recommendations, is weak because it lacks these provisions: - A requirement that drug manufacturers meet specific production standards. - A requirement that all drug advertising contain a "MORE ECONOMY" Jfr Day or Night Service Cemetery, Mortuary, 3l2 .. j A FEW CATS AND DOGS that need a new home 33c HAIR NETS Popular Shades Pkg. of 6 49c INSECT FOE Qc1 liquid Bug Repellent gjf 25c DR. BERRY'S Qc Complexion Soap 69c SKEETO-GO H Qc Iniect Repellent Stick I 3r 60c AMO-REX I Qc Ammoniated Tooth Powder I I9c ATLAS COMBS Qc Curl or Pocket Type Sf 35c Combo Comb-Brush 1 Qc All On One Handle 35c Goldie Shoe Kit Qc 6 Individual Shine. 25c LADIES' FOOT-SOX Qc Clote Out Price 98c Wrisley Bath Set i)Qc Miniature Coimetict Jtr 98c BUBBLE BATH AAc Disney's Colorful Animals INTRODUCING PERFECT-PAN BLACK & WHITE FILM FINE GRAIN PANCHROMATIC 620 120 127 3 2 IN 1 FILM BLACK & WHITE OR COLOR 620 120 127 79 - WE STILL HAVE NICE TOYS AT Vi Free Delivery in Medford Y" cI5tp.au fJESqd description of any side effects. - A requirement that a new drug win positive FDA ap proval before it can be sold. This would replace the pres ent practice of letting a man ufacturer sell a medicine un less the FDA raises an objec tion within a specified period. f m Memorial Park & Funeral Home "A Name To Trust" 773-7338 Mausoleum, Cremations REMEMBER Prices listed in our XMAS in JULY SALE Are in effect through Aug. 1 1th Rons 823c FREE DEVELOPING ON 2 IN 1 FILM THROUGH SEPT. 1 A QUANTITY OF PRICE OR LOWER OPEN WEEK DAYS 8 TO 9 SUNDAYS 9 TO 2
