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News King County Health: More Potent TB Strain Spreading General population in Seattle is increasingly at risk from antibiotic-resistant, communicable disease K ing County, Wash., public health officials say a strain of tuberculosis, called PCR0001, which is responsible for 76 cases in the local homeless population since 2002, is now being transmitted among the broader community as well. Health officials say they’re wor- ried because the strain appears more likely to infect others and cause active TB disease than the more commonly seen strains. “We aren’t immune in King County from the global epidemic or the changing nature of the dis- ease itself,” said Dr. David Fleming, Director and Health Officer for Public Health - Seattle & King County. “The wider spread of what appears to be a more potent strain is concerning, and it’s an important example of why we can’t afford to relax our efforts in controlling TB.” Tuberculosis, also called TB, is an infectious disease caused by a bacterium named Mycobacterium tuberculosis. TB often involves the lungs (pulmonary TB) but can infect almost any organ in the body. TB is almost always curable with antibiotics that are readily available in countries such as the United States. People with active TB disease are made sick by bacteria that are active in their body. People with inactive, or latent, TB infection are not sick because the germ is inac- tive inside their body, and they cannot spread TB infection to oth- ers. Of the 116 active TB cases diag- nosed in King County in 2010, six were caused by the PCR0001 strain, including three outside the homeless population. The TB Control Program has made focused efforts in recent years that have helped to control the spread of the PCR0001 strain among the homeless population, and is now prioritizing its work on controlling the spread of the strain more broadly. Approximately one third of the world’s population is infected with tuberculosis, and two million people die from it every year. King County’s active TB rate is consistently among the highest for any local area in the country, reflecting the global nature of King County’s community. Of the 116 people diagnosed with active TB in 2010, 84 percent were born outside the United States. Public Health – Seattle & King County’s TB Control program ensures that people with active, or infectious, TB are diagnosed and treated until cured. They also evaluate and treat, if appropriate, people exposed to infectious TB, so it does not continue to spread. Everyday, TB program staff ensure that infectious TB patients adhere to drug treatment, which consists of multiple medications for six months or longer. More than 2,800 clients make almost 12,000 visits to the TB clinic annually for treatment. The TB Control Program also evaluates immigrants and refugees who are suspected of having active TB. However, because of state and King County budget crises, the TB Control Program faces contin- ued funding challenges. Over the past several years, the TB Program has reduced staff and now limits services to the highest priority cases and contacts. “We estimate approximately 100,000 people in King County have latent, or dormant, TB infec- tion. While they aren’t contagious now, some will develop active TB in the future and could infect oth- ers,” said Dr. Masa Narita, TB Control Officer for Public Health. “TB is curable and preventable, but controlling TB is an ongoing challenge, especially with fewer resources to protect the communi- ty.” Highlights of 2010 TB data: 116 people were reported with active TB, for a rate of 6 per 100,000 people, a decrease from 130 cases in 2009. This was noticeably higher than the U.S. rate of 3.8 cases per 100,000 peo- ple. 84 percent of infected individu- als were born outside of the United States. Of these individu- als, 67 (62 percent) came from David Flemming five countries: the Philippines, Somalia, Ethiopia, Vietnam and India. People of color continue to have disproportionately high rates of TB, with the highest case rate among individuals who identify their race as black (26.4 cases per 100,000) or Asian (21.4 per 100,000). 20 people (17 percent) treated for active TB were resistant to at least one TB medication. Two multi-drug resistant TB (MDR-TB) cases were diagnosed in King County in 2010. Multi- drug resistant cases are much more expensive to treat, costing up to $250,000 each. To view the 2010 summary data and for more information on Public Health’s TB Control Program and activities, visit: www.kingcounty.gov/health/tb. And now you can add your own announcements, events and public services to The Skanner Website. Just go to http://www.theskanner.com/your- beat and register. Page 10 The Portland Skanner march 30, 2011