The Oregon daily journal., March 21, 1910, Page 4, Image 4

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THE OREGON DAILY JOURNAL, PORTLAND, MONDAY EVENING. MARCH 1, 1910.
TEDIOUSMETHODS
OF TESTING DRUGS
HI 1 RESULTS
Many Animals Sacrificed fo
Good of the Cause; Drugs
Taken From Animals; Vas
Profit on Medicines.
Hy Fr-rlc J. Ha..kln.
Washington. Marrh 21. IJvoly In
' tereat In frlnK shown in th forthcom
ing iWonnlnl revision of the I nlte,l
Statos l'hnnna.'..wla. The doctors,
the rtnimclotn. th pharmaceutical as
aoclattona. the Rnvwnmonl In Khort
every one of th many interrsts that
bear a close relM!in to riruira from the
time they am In their raw state until
they pas down Iho throat of th r
tlent ar- all taking much tntrent In
the revision. Even congress has ha'l
t?ll tnaU.-r I.WmgM "hefnre "1! thr.tntrh a
bill which proposes that the I'hnrma
copoela shall be mdf a i.rop.rty of
the government, to be rnvlaod under lis
control. It is aald that the drug man
Ufacturers are In favor of such a law.
but that all other interests are heartily
against It.
The ninth decennial convention for
revising the Pharmacopoc la will In a
manner leRlslate for congress, .since
that bodv has said In the. pure food
law that the I'nited States Pharmaco-
poeia and the I'nlted States nispensa
, tory ahall be the official standard of
preparations under the pur food law.
And here an interesting point has been
raised. One state has hold In its hljrh-
est courts that the official drug book
at the time nf the enactment if 'the
law remains the official book. On the
nther hand another state ha held
through its courts that the book In
force at the hour of Interpretation la
to govern. ' Bo far a Is known the
federal courts have not passed upon
the subject, but most authorities are
acting on the principle that the time
of Interpretation and not the time of
enactment will serve to fix the stand
ard.
40.000 Pharmacists.
There are about 40,000 pharmacists In
the United States, and they prepare
about 1,000,000 prescriptions every day
tn the year. The ordinary range of
prescription writing takes In several
thousand drugs and proprietary com
binations. The highest number of sub
stances resorted to In the important
drug 6tore Is about 10.000, although
there are 60,000 drugs and compounds
known to the pharmaceutical world. In
record of the preparation of 17.000
prescriptions it was found that 1777
different drugs were used, and that the
average number in each prescription
was 2.6. Opinions vary widely aa to
how many drugs a physician really
needs to prescribe. Dr. Osier i nee aald
that nux vomica and hope were the
only two really eaaentlal things, but of
course he was using a hyperbole to
, (drlve home an argument against the
Excessive list of medical preparations.
Some physicians think that 100 drugs
are sufficient to quell the whole ga
mut of human ills,, while others com
plain that the Pharmacopoeia Is not
comprehensive enough when It con
tains only 1000 official preparations.
Beeklag Wew Medicines.
The preparation nf drugs constitutes
one of the most Interesting things in
all human activity. The minute care
1 ji
that la required In the preparation of
the heroic remedies grips the attention
of the layman as firmly aa ihe won
dera of astronomy or geology. Drug
manufacturers ransack the whole world
for new Ideas In healing materials.
Medical science owes its us of stro
phanti, one of the most valuable of
the heroic drugs, to tne study or a
poisoned arrow from Africa. In the
preparation of thla drug Its strength
must frequently be tested, and In this
teat a live frog Is used. The standard
la the amount It requires to kill a
frog weighing a certain number of
ounces. Tho hundred thousandth part
of a grain will determine the Issue
between life and death for ihe frog.
Testing Drugs.
Ergot Is nothing more than a fungus
growing on rye, and Is gathered
throughout the rye field of Europe.
The only known way to satisfactorily
test the strength of ergot la to paint
a rooster's comb with It. If It makes
(i certain shade of black the prepara
tion Is of the required strength. Every
manufacturer of ergot has a coop full
of roosters to aid lilm In his tests of
strength In the case of digitalis It
Is llternllv "tried on the dog." A dog
Is anesi hftlxed and given a dose of the
medicine. His heart Is men cut our
and placed In a gauge If the expan
sion fills the gauge properly, the drug
Is known to have the proper strength
Andrennlln comes from the suprare
nal glnnd of animals, a llttlo gland at
tached to the kidney. It Is one of the
most pnwerrui or drugs, on" imimwnu
of a grain for every two pounds or
body weight having a vast effect on the
human system. Pepsin, -which Is the
prepared linings of pig stomachs, will
digest from three to four thousand
times Its own weight In hardhotled
eggs. In one raciory mere is iian mi
acre of glass In the drying closets that
Is cov ered over with pepaln all the
time.
Kan's Likeness to Monkey.
If Darwin had lived to the present
day he would have had much stronger
proof of his theory of the close rela
tionship between man and monkey. He
would have gathered it, not from the
anthropologist, but from a test In the
chemical laboratory that has been de
vised to detect the presence of human
blood. Quantities of human blood are
Injected Into the blood vessels of a rab
bit at intervals for several days. This
makes the little animal feverish and
restless. After a certain time has
lapsed the "humanized" blood of the
rabbit Is taken, and It will produce cer
tain well recognised effects when ap
plied to any blood other than that of a
human being or a monkey.
In dogs, cats, guinea pigs, horses snd
all other animals, exvept men and mon
keys, this reaction will take place. With
monkey blood It behaves exactly as
with human blood. In tests to discover
the presence of human blood, the merest
trace of It will stand revealed and
positively Identified.
Cornering Drag Market.
One would suppose that the drug mar
ket would be Immune from the attacks
of the man who seeks to "corner'1 some
thing, but as a matter of fact nowhere
else Is the opportunity so great and so
much Improved. Where it may take
J10.000.ono to corner the wheat market,
a few nundrea tnousann doners win
effectively corner the market on a given
drug. Then the operator is ready to
name his price, and often he sells at an
advance of from 100 to 300 per cent.
As the prescription charges of the
average druggist remain the same year
In and year out, the advance comes out
of his pocket.
Just now there Is a war on between
the doctors and a certain association of
druggists. About 12,000 druggists have
formed a syndicate for the compounding
and aale of a line of preparations made
from the best prescriptions that have
come to them In the course of business.
DOUBLE WRECK N
EM N OREGON
Engineer Risk and Fireman
Hopple Killed; Freak of the
Block Signal System.
("pedal Dtapatrk to The Journal.)
Pendleton, Or., March 21. Two men
killed, two engines demolished and
seven freight oars piled in a tangled
mass, are results of a double wreck
eight miles east of thla city on the
O. It. A N. at 7:45 yesterday morning.
Engineer L. Risk and Fireman Hopple,
both of Ia Orande, who were running
an engine and tender down grade east
of Cay use, were killed.
The disaster was caused, presumably,
by the reckless speed at which the en
gine was rounding a nine degree curve,
throwing It against a steep embank
ment with such force as completely to
demolish It.
Engineer Risk was pinioned by one
ami and literally scalded to death, while
Fireman Hopple whs burled under tons
of coal, from which his body was re
moved only after several hours' work.
Both were unrecognizable.
Twenty minutes later extra freight
No. 885 westbound bore down upfrn
the scene. As the wrecked engine and
tender were clear of the rails the block
signal registered a clear track, and the J
train crew were unaware of danger
ahead until almost upon the wreck.
Engineer Walter Robinson, Rrakeman
W. L. Rose and Fireman l". L. Wilson
Jumped as the nose of their engine
struck the wreckage. All three escaped
uninjured. Their engine, followed by
seven freight cars loaded with steel
rails, coal and cement, plunged Into
the I'matllla river A wrecking crew
was sent out at once.
The dead men were brought to this
city by Coroner Folanm.
IN 0. Ill HAS
4TH BIRTHDAY
Favorite Grandson of Oil King
Will Have Prospective For
tune Diminished.
cities have boycotted the druggists who
carry these goods. In many cases It has
sufficed to bring the druggists to terms.
Vast Profit In Medicines.
That there Is a vast profit In pro
prietary remedies is shown by the cen
sus figures. In a certain year It was
found that the wholesale value of
patent medicines was 7f,000,000, and
that the cost of the materials entering
Into their manufacture was 121.000.000
- a gross profit of nearly 300 per cent
Tin; retail price was more than double
this amount. One of the strangest
anomalies of the scientific world Is the
fact that while every physician who
prescribes must be licensed after a rig
orous examination, and every druggist
who fills the prescription must undergo
a like examination, any man, without
let or hindrance other than the limita
tions of his own means and ability, may
go into the business of making and sell
ing proprietary remedies and manufac
turing drugs. He has the life and death
of thousands of people in his hands, as
Improperly standardized drugs may re
sult tn the dpath of all who use tbem.
In some cases, as in the antitoxin for
rabies, the federal government has taken
Jurisdiction over the preparation, but In
the great majority of cases the people
have little to protect them except the
reputation of the manufacturer.
Drugs From Animals.
In the matter of biological nrenara-
They advertise widely, declaring that Itltlons the homeopathic pharmacopoeia
is foolish to pay a doctor's fee and a j makes use of a wider range of sub
prescription fee when Just as good a stances than the allopathic school. In
remedy may be had for less than the j the former one finds ambergris, taken
prescription would cost. Of course the from me intestines of the sperm whale.
doctors do not like this, and in some fresh fox liver, fox call. di'Vd fox luncs
cruaned honey beefe, bee (sting poison,
fresh cockroaches, spider webs and even
bedbugs. No data la at hand as to the
manner of collecting the latter or the
prices paid.
Some Statistics.
It Is said that tlierp arc more than
3000.000 people seriously 111 In thn
United States every day of the year.
One visit out of every three a doctor
makes results in the giving of a pre
scription. It Is stated that not one
physician in five possesses a copy of
the United States Pharmacopoeia al- j
though every prescription that he ls.es !
New Tork, March II. Tt John t
Rockefeller carries out his Intention to
give away the hulk of his enormous for
tune by establishing a gigantic founda
tion for philanthropic purposes, his
grandson. John D. Rockefeller III, who
completes his fourth year today, will
lose the distinction of being the richest
baby in the world, or. expressing it
nioro correctly, of being tho baby with
the prospect of Inheriting the largest
fortune In the world. It Is true that
even If the Rockefeller foundation be
comes a fact the favorite grandson and
namesake of the oil king will Inherit
enough to keep the wolf from his door
for the rest of his life, but his inher
itance will not be as great as that of
several other grandsons, whose grand
tathers have accumulated and are still
accumulating gigantic fortunes In oil,
steel or railroads.
However, the possibilities of the fu
ture do not worrk John D. Rockefeller
III at present. He was a remarkably
large and healthy baby when he was
born, on March 21, 1908. and under the
strict hygienic regime enforced by his
father has grown into a fine and
healthy youngster, vigorous and full of
life. Unconscious of being the pros
pective heir of untold millions, and
equally unconscious of the probability of
having his share of the Inheritance ma
terially diminished, he celebrated his
birthday today with all the lest which
a boy of his age, be he millionaire or
pauper, can put Into such a celebration.
rsTorlte Grandson.
John D. Rockefeller has many other
grandchildren. but John D. Ill has al
ways been his favorite, and it has al
ways been understood that the hulk of
his fortune would some day descend
upon the eldest son of the oil king's only
son. It has always been a subject or
Interest to some persons with a mathe
matical turn of mind to figure out how
large would be the fortune which John
D III would some day Inherit. Nobody,
perhaps not even Mr. Rockefeller him
self, knows the amount of his present
wealth more than approximately. It
has been variously estimated at from
IL'OO.OOO.OOt) to ll.nOO.OOO.oOO, and some
men well acquainted with the affairs of
the oil king have expressed the opinion
that even the larger amount is a con
servative estimate.
Accepting Jl. 000, 000, 000 as the basis
of their calculations, mathematicians
have figured out that this amount at
simple Interest of 3 per cent would hava
grown to ,$:!.5io.noo. i0(i n 50 years. Rut
of couise the establishment of the Rock
efeller foundation would alter the situa
tion. The wealth would probably In
crease at a moderate rate. In spite of
the benefai Hons distributed by the foun
dation, as only the Interest of the en
dowment would be used; but the bulk
of that tremendous fortune would not be
in the hands of John D. Rockefeller III,
although undoubtedly he would succeed
his father In the control of the fund.
RATE WAR ON ALASKAN
STEAMSHIPS TO END
Our Spring Clothing for Boys shows case of fit,
security of style, and is absolutely guaranteed for
endurance qualities. Why take chances when YOU
KNOW that here you can get reliable
BOYS' SUITS FROM $3.50 to $15
(I'nltpd Prpaft I.eHNPri U'lr 1
t Qnattlf, lVah torh "1 T),a n .4
the passenger rate war on Alaskan
steamship lines is in sight. It Is gen
erally conceded on the waterfront to
day that rates will be back at the old
basis by April 16, following the an
nouncement of the raeific Coast Steam
ship company yesterday that the old
ratis would be restored April 1.
This Action is the result of an ex
pected heavy traffic to Alaskan points
out of Seattle this summer. Booking
for berths and business already blocked
out Is the basis of the expectation of
nn unusual traffic.
Chinese Sailor to Prison.
EASTER MARCH 27tlr
LION CLOTHIERS
166-1TO Third Street
(I'nlted Press Leased Wlr.
Prince Rupert. R. ('.. March 21. Ah
Is supposed to be based on that work, i 'pV. a Chinese sailor on the ship Cape
I Most doctors possess dose books which: f-reton. is on nis way to me ."sew West-
iglve them the data without reference minster penitentiary, with an officer,
to the pharmacopoeia.
Several new medical preparations are
being placed on the market every day.
One big drug manufacturing concern
spends a quarter million dollars a year
on Its laboratory. Here trained scien
tists are trying to evolve new things for
the good of humanity. One man lias
spent years in trying to make a perfect
germicide. Another spends years In ex
periments with pneumonia serums.
AVhlle physicians have made many of
the valuable discoveries in the realms
of medicine, .the majority of These have
recently come from the laboratories of1
drug manufacturers. j
Tomorrow Preventing Accidents. !
RHODES SCHOLAR WINS
12 A HURDLES
We Give Away
Absolutely Free of Cost
The People's Common Sente Medical Adviser, in Plain
English, or Medicine Simplified, by R. V. Pierce, M. D.,
Chief Consulting Physician to the Invalids' Hotel and Sur
gical Institute at Buffalo, a book of 1008 large pages sad
over 70Ilutration, in strong paper covers, to any one sending 21 one-cent
tamps to cover com of mailing only, or, in French Cloth binding for 31 stamps.
Over 680,000 copiea of this complete Family Doctor Book were sold in cloth
binding at regular price of $1.50. Afterwards, oae and a half million copies
were given away a above. A new, up-to-date revised edition it now ready
lot mailing. Better send NOW, before all are gone. Address World's Du
Mnsaby Mcdical Association, R. V. Pierce, M. D., President. Buffalo, N. Y.
DR. PIHRCE'8 FAVORITE PRESCRIPTION
THE ONE REMEDY lor woman's peculiar ailments good enough )
that its makers are not afraid to print on its outside wrapper ita
every ingredient. No Secrets No Deception.
THE ONE REMEDY for women which contains no alcohol and
BO habit-forming drugs. Made from native medicinal forest root
of well established curstive value.
London, March 19. V. McDonald,
formerly of Camnrldfre, Mass., and now
a Rhodes scholar at Oxford, won the
120 yard hurdles at trie annual inter
varKlty meet of Oxford and Cambridge,
on the Queen's club grounds Saturday.
Ills time was 14 seconds.
rive American Rhodes scholars were
among the entries for the meet. These
included I,, c Hull, formerly of Uni
versity of Michigan, and now: president
of the Oxford 1'nivcrslty Athletic club,
who won the BOO yards and 440 yards
i tin In the games last year. E. O. Put
nam, formerly of the 1'nlverslty of Kan
sas, and R. E. Blake, formerly of the
Vandcrhllt university, Nashville. Tenn.,
are Oxford entries in the weights.
CORONER'S JURY GOES
TO WELLINGTON TODAY
ffnttod Prrn I cifj Wire
Seattle. Wash.. March 21. The coro
ner's Jury Investigating the Wellington
avalanche left for Wellington hv sne-
I cial train at 9 o'clock this morning.
j headed by I'oroner J ( '. Snyder, to com
plete the taking of evidence. The Jury
! will leave Wellington mi the return at
:9:S0 tonight and wll I "probably reach its
j verdict before arriving In Seattle.
j" Strange cases of mistaken identity
continue to crop out in the lnijuent. K. !
XV. Holes of Maybeny, Ont., twice re- '
j ported dead In the wreck, appeared be- j
fore the Jury Saturday tn testify. He!
had walkei to Scenic the day before 1
' tire slide.
j Joseph Benier. n timber cruiser, 1
j walked tn'o the morgue yesterday and
j locked at a corpse tagged "Joseph Be- '
nler. No. S3."
"Som mistake." said Mr. Benier. "I j
missed the train."
to serve a three years' term, while a
Lump In
Your
Stomach
, Stuart's Dyspep
sia Tablets will
dissolve It at
once.
Enjoy every meal.
Eafyourfoodwith
zest. Don't kill
your stomach.
Keep it alive and
I properly working
Send for the free
trial package. F.
A. Stuart Co., 150
Stuart BldfJ. Mar
shall, Mich.
Sold by druifilsts every
where. 50 cts. full sized pktf.
BOYS-
ENTER CANOE CONTEST
200 Votes Free
A. B. STEINBACH & CO.
THIS WILL INTEREST MOTHERS
Mother Gray's Sweet Pmrdert for Children, a
Certain relief fur KetertKhnew, -Headache, Bnil
Stomweh. Teething Olsnrders. moTe and regulate
thp Bonel mid destroy Worms. They break up
( nlda In 24 boors. They are ao pleasant to the
tantc and harmless a milk. Children like tbem.
tiTfr 10,'aJO testimonials vt cures. Tfc.y never
fail. SnM by all drnialsu, 2ftc. Ask today.
Don't accept any substitute.
1500 head tax, paid by the captain of
the ship, la In the local government
treasury. ''.'
Ah Wey. together with other Chinese
sailors, started a small mutiny on the
hip. In which the right hand of a fire
man wee almost severed with an axe.
Judge Young sentenced Ah Wey to
three year and let his countrymen go
free.
As Constable Leek took hie prosoner
from thaihlp, Collector MacDonald of
the Canadian customs service demanded
the 1(00 head tax. Captain Warden re
fused to i pay, and Ottawa wis appealed
to by wire. The department there sus
tained the looal collector, and Captain
Warden waa compelled to pay the $600
before his ship was granted clearance
papers.
Journal Want Ad bring results.
i To. Try Ont SubmarlnM. ' j,
Boston, March ItSeven hew iitib
marines, the Tarpon, Stingray, (Jraylinr,!
Salmon, Bonlta, Narwhal, and Snappnfaia I
known officially aa tho third ubmarffij
flotilla, left Charleston navy yard today
for Newport, under escort of the cruiser
Castine. During April and May the sub
marine will be tried out ln Narragan
aett bay preparatory to the Joining of
the Atlantic fleet for the aummer drllla.
NEW DEPARTMENT
READY-TO-WEAR
GARMENTS
FOR
LITTLE WOMEN
MISSES AND GIRLS
TAILORED SUITS. COATS, DRESSES
TAILORED WAISTS, RAINCOATS
ENTIRE THIRD FLOOR
EVERY QARM.ENT THIS SEASON'S
PRODUCTION.
TDTPTVT QXPT T TTXTP LEADING
aDlM kJ.O JLJJLJXx M VaJT CI .OTTTTER
ro oo,
oo,
flO.
r o
c-tyw t
look
for
The Purest None too Good
Children require the purest of food. No mother
would knowingly sacrifice the health of her child
ren. If you would choose discriminately ask for
HAMS
!5 BACON
BRAND
You can feed it to the children knowing that it is per
fect that it has passed government inspection and
bears the stamp of approval. They'll like it too!
At Best Dealers. Hotels and Cafes
UNION MEAT COMPANY, PORTLAND, ORECON
PtosMer Packer of the PadOe