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About The Oregon daily journal. (Portland, Or.) 1902-1972 | View Entire Issue (May 17, 1908)
' . VMS! e m . X "VrfA N vfC yT -v'H M K AP-A TheMysteriousGland That Ha Science to a iscovery HERE is one great question now agi fating the medical profession: Has the seat of life b e e n found at last? li the whole science of medi cine to be revolt' lionized by the discovery of the functions of a body in the hu man organism about uhich as little has been known in (lie past as about the per plexing appendix, that has caused so much trouble? An impossibility a ludicrous impossi bility of course, many will assert prompt ly. Galen and Hippocrates have been too long dead, Metschntkoff and Koch too long alive, to make the idea anything less than laughable. Yet, denuded of its scientific phraseol. ogy, it was precisely that which brought together, in Philadelphia, a short time ago, the two great national bodies, the American (Therapeutic Society and the A merican Phar maceutical Association. They joined to hear, from the lips of Dr. Charles E. de.M. Saoust a discourse on "The Auto-Protective Resources of the Body: a New Foundation for Scientific Therapeutics." For the first time, although heralded with the most earnest indorsements by the most authoritative medical journals of this country and of Europe; although advocated by some of the most distinguished medical authorities known to science, the epoch making discoveries of Sajous have impinged upon the attention of the profession in a manner which compels recognition of their magnitude. And this article is the first that brings before the world at large any knowledge of the wonderful promise, for health and iife, which exists in this outcome of twenty years of the most patient investigation and the most arduous labor. JUST here the' head restsupon the coltrtnn of the spine, directly under the human brain, is located small gland towhich . science succeeded in giving a name, and . nothing more. : ' Science called it the pituitary body. "' Sci-; ence supposed it secreted something or other; -but what it secreted! how it secreted, and why it -secreted, science did not know, and, until Sajout took up his stupendous labors, science did not care. . " Science cares now. Sajous' work has dem onstrated that it is the last, .secret stronghold of the life of man; and the fluids which the pituitary body produces are those which gov ern, the products of the adrenal system, whose functions, Sajous had to demonstrate, likewise, in their .truealue.-v'V: 'i ;";;.. v : - V Fort the adrenals, withi - other ' ductless glands are really the things that dominate the human body, and control the "noble organs" th heart, the lungs, the liver on which science;- uio.iwsnroiung - JUocated on the very-: ton. of. tlw tniml column, ImmloUately below, the- brair protected 1 V - y PORTLAND, OREGON SUNDAY HORNING, - HAY'. 17, ; 1903 ' . ': fv: jl 41 -1 Startling ,Mf5yl H i: v.' ' .JJsaj-,-- V . . .- ... I' I 11' I mini II 'Hi 11 11 'HI! I ' fj on ; all sides . with. , the Outmost j -care, " lies taeV pituitary body.' ? To its; role in- theeconoiny of the human, bod a recently published 'text-book oi ' pnysioiogy. devotes seven . lines, tes seven. lines. Indeed, be- yoad .the fact that it was suDnoscd to nrovids , ""w oracuuiF-uiB purpose oi wnica : had never beei" ioundT-notWhg Was' kliown' as to" the" actual 'role, of ite fo'rwlrd ' lobe'; .whiie its - ' posterior lobe had been" relegated,' to-'tho! rahk'of Saious- demonstrates ; not onLvthat : this foncention is false; but that the nituitarv bodv. . in lis reiftiiom to tne iuncuous 01 mo duuj at ;large;is itself. Xone of these functions is impaired when the cerebral hemispheres of the brain are removed; all cease, however, when the pituitary body is submitted to the sume removal. The brain, as the organ of mind, can utilize the epinal system, with ;,hich it is connected, to execute its mandates; but the spinal system is also supplied with its own brain, the pituitary body, which Sajous terms the somatic brain, the poverning organ of all vegetative functions. He shows, moreover, that this somatic brain con tains a delicate organ whose mission is to pro tect the body against disease. Sajous studied this organ in the animal scale, and found it in all animals down to such low forms as moll us ks, where it bears a sugges tive name given to it by zoologists, the test organ, or osphradium, and is known by them to have the function of testing the water for these lowly beings as they pass through it and take it in. In the higher vertebrates, including man, this test-organ protects against disease. . Thus it is asserted that in the "somatio brain," in the pituitary, body in that new and tiny brain of the human being whose functions Sajous has at last discovered lies the ultimate seat of human life, lies the citadel which is the very center of the agents that guard against the destruction of life. .... Sajous found that the adrenals two small capsules above the kidneys, first comprehended in their importance by Brown-Sequard were provided with a center situated at the base of the brain. This, he subsequently . ascertained, was a nucleus of cells in the posterior lobe of the pituitary body. That nucleus received nerve fibers from the sensitive test-organ. HOW THE BODY IS PROTECTED The manner in which any" poison or toxin can increase general oxygenation? became ap parent: it excites the test-organ, and this struct ure, in turn, through nerve-paths, increases the activity of the adrenals. Thus the bipod is provided with an excess of adrenoxidase, one of the constituents .of the body's protective sub stance, auto-antitoxin. But the metabolism, or chemical changes by all organs, being rendered unusually active by the excess f adrenoxidase in the circulating blood,- the formation of leu c6cytes, or white cells !ini the . blood, is stimu lated, and "the . proportion ''of their product in the blood is correspondingly increased. ' The secretions of the :pancreas, an im portant gland near the stomach, being also stim ulated by the ; excess pf - adrenoxidase, more trypsin is produced; and we thus have the.three components of 'the body's protective fluid auto antitoxin, theoxygen-la4en adrenoxidase ; and the phpsphoTus":!aden '-products pf " the blood's-; white cells to; supply the increased heat-energy . required Jto senable-the trypsin to destroy bac-; teria, their toxins, or any other poisonous agent "; which the blood may contain. :- ? : A comprehension Vof the ' essence of , 'Dr. Sajous' discoveries' can, however, come best from the words of DrT J. Madison Tayjor, for five -years his associate in . the editorship of ' The ilonthlv Cyclonedia of Practical Medicine. Dr. .Taylor,- remarking that.'Dr. Sajous', wbrkv-was. conceived- after - a unique medical- editorial ex perience, said that all current literature from all countries has been utilized, .as well as thou sands of direct manuscripts and treatises, in various languages, from high authorities. v "The chief among the working principles which he has welded into a concrete whole and has made available," 'said Dr. Taylor, "is that, in understanding the natural history and phe nomena of disease, we must bear in mind that the great organs hitherto .regarded as dominant and known as the 'noble organs euch as the heart, tho lungs and the liver are really sub sidiary to the true .dominant organs,' that is, to the ductless glandf which are the--adrenals, .the thyroid and the pituitary bodies. "These constitute a controlling system which exercises a regulative' action upon the subsidiary orgaii3, . constitutingAtho- keyi3yitaJ processes. ,;' - " MANY MYSTERIEStSOLVED Tni-estimating not nlythesigmficanceol '. phenomena, but the action of . remedies, it 4sr ' necessary to bear in mind that, whatever ap.' , parent actions- areevolved, theoessentiwVagenciea -are those n?Mchnharu:)ryiepre59KthaNiadrenal system. ' "A numberfKbserver3aveadeijplaii , that the secretion of the adrenals is the chief r factor in regulating tho caliber f the blood vessels, the ebb and flow of body fluids. Dr. - Sajous has shown that hepivotal gent,istthia , adrenal secretion, which sustainsthe-chieferol9 -' in the distribution of oxygen. ' . ' "It is to this analytic work that'Sajousowevi the discovery that the underlying, cause of the 1 existing confusion in medicine was due to the prevailing lack of knowledge concerning , the functions of the ductless glands; it was his i Bynthetio work which led him to the discover of the true Tole of these organs in the body. - "As soon as these functions had oeen ea- tablished by him, hundreds of problems, ninety-... , six of which he enumerates in the introduction , to his second volume, found a ready solution, the experimental results of a multitude of in- , vestigators thus falling into line, as it were, of their own accord. "Pulmonary and tissue .respifation, ab . sorption and nutrition, tho circulation of the nervous system, the nature of organic function and the manner in which it is awakened, the composition 'of ' ferments, the production of sleep, are . but a few of: the - many problems r which physiologists had admittedly failed to SOlve. ' , ''? ":S'v"v-.-'-".'-:-'. . .- "TTheil once all these problems were solved, and the- solutions proved correct by the pre cision with which they all harmonized, a su perb mechanism .revealed itself to Sajous; that pf the human organism complete, the function ' of the ductless glandss andthe presence of their , ; products in. all organs having filled many da- . plorable gaps those identical 1 functions which physicians and ' histologists, notwithstanding - their painstaking laborst bad failed to explain. 'i , "Sajous found ,that the adrenals supplie 1 ; ''a secretion which passed to the lungs and took up therein the oxygen of , the, air. This solved the cardinal problem of human. functions: that lof pulmonary respiration. He discovered an vother important fact in this conue-tion, thaS V- . (CONTINUED ON XXSIt)IJ TAGK.) v-.. V, Vv ir: