t
Doctors Can Know
Nitroglycerin Role
Inside Human Heart
Delos Smitb
By DELOS SMITH
" UPI Science Editor
. New York -(UPS- Every doc
tor knows nitroglycerin can
do big things inside human
hearts. But
now, for the
first time, all
doctors can
know just
how this
working
s? chemical com-
pound of dy-
namite does
them.
' This news
from inside human hearts be
longs to Drs. Norman Brach
feld, John Bozer, and Richard
Gorlin who got it by running
instrumented tubes through
arteries and into hearts.
The technique is quite safe,
relatively new, and is piling
up more and more inside
knowledge of the most pub
licized and sentimentalized of
our organs.
The hearts belonged to 10
men. Four were normal and
the other six had only minor
defects. Once the tiny-diameter
tubes were in place, the
men let a nitroglycerin pill
dissolve under their tongues.
Offer Less Resistance
Almost immediately their
heart muscles began taking
more oxygen out of the blood.
The flow of blood through
the hearts increased and the
scientists "presumed" this was
caused by the increased oxy
gen consumption.
At the same time, the heart
blood vessels enlarged and
thus offered less resistance to
the flow. of blood. But the
work rates of the hearts re
mained unchanged which
meant the work was done less
efficiently.
Nitroglycerin is one of the
most commonly prescribed
heart medicines. It relieves
the choking sensation of an
g i n a or "coronary insuffic
iency" and the crises of very
high blood pressure so quickly
that persons given to those
conditions carry the pills with
them, just in case.
But for such a widely used
About three-fourths of the
states engage in growing to
bacco crops.
medicine, very i ti 1 e was
known 'about how it worked.
The scientists, who work at
Harvard Medical School and
the U. S. Navy hospital at
Portsmouth, N. H. were the
first to study nitroglycerin in
its direct impact on human
hearts. .. '
Stretches Blood Vessels
Since its effect on the heart
was discovered in 1867, it has
been classed as a stretcher of
heart blood vessels, and that
it is, of course. However,
Brachfeld, Bozer and Gorlin
showed this was a secondary,
effect and its big effect was
to increase oxygen use by the
heart muscle.
From the medical x stand
point the importance of this
was the demonstration that
nitroglycerin is not "a pure
dilator of heart blood vessels,
because "a pure dilator"
would enlarge the, . arteries
without changing the heart's
rate of using oxygen. Under
many circumstances, tnat's a
useful thing for doctors to
know.
Previous studies were han
dicapped by less exact meth
ods and the necessity of using
animal rather than human
hearts. As a result, their find
ings were often contradictory.
And so the picture was any
thing but clear and many un
supported assumptions were
being made as to what nitro
glycerin didn't and did do in
side hearts. The scientists re
ported their clearing of the
picture to a technical organ
of the American Heart associ
ation. '
Centennial Offers
Son
ething-forrEveryone.
MAIL TRIBUNE, Medford Or.
Thursday, May 21, 1959
LEGAL NOTICES
LEGAL NOTICES
NOTICE TO CREDITORS
IN THE CIRCUIT COURT OF THE
STATE OF OREGON FOR JACK
SON COUNTY
PROBATE DEPARTMENT
In the Matter
of
the Estate of Frank A. Dufek,
deceased.
NOTICE IS HEREBY GIVEN that
I have been appointed Executrix
of the above estate by an order
made therein on April 28th, 1959;
all creditors having claims against
said deceased are hereby notified
to present the same, duly verified
and with proper vouchers attached,
to me at the office of Roberts,
Kellington & Branchfield, 201-5
U. S. National Bank Building, Med
ford, Oregon, within six months
from the date of this notice.
Dated at Medford, Oregon, this
30th day of April, 1959.
Lesta Dufek
Executrix
NO. 10351
NOTICE OF HEARING ON FINAL
ACCOUNT
IN THE CIRCUIT COURT OF THE
STATE OF OREGON FOR JACK
SON COUNTY
In the Matter of the Estate
of
JOSEPH FRANKLIN, Deceased.
NOTICE IS HEREBY GIVEN that
the undersigned has filed her final
account as administratrix of the
estate of Joseph Franklin, de
ceased, with 'he Circuit Court of
Jackson County, Oregon, and that
said Court has set the 15th day
of June. 1959, at the hour of 10:00
o'clock in the forenoon of said day
in the Court Room of said Court
in the Court House Building at
Medford, Jackson County, Oregon,
as the time and place for hearing
objections thereto and the settle
ment thereof
DATED and first pubiisnea tnis
14th day of May, 1959.
Jean L. Franklin,
Administratrix
HARBISON AND PIAZZA
Attorneys for Administratrix
NOTICE OF SALE
Notice is hereby given that on
the 29th day of May, 1959. at 10:00
O'clock A.M., at the front door of
the Jackson County Courthouse in
Medford, Oregon, I shall- sell at
public auction for cash to the high
est bidder, all the right, title and
interest of Joseph Ellsworth Dame
wood and Edna M. Damewood, in
the following described real prop
erty, to-wit:
Beeinnine at the Southeast cor
ner of lot 2, Block 1 of the River
side Addition to the City of
Gold Hill, Jackson County, Ore
gon, according to the official
plat thereof now of record;
thence North 77" 20' West 81.8
feet; thence North 12 40' East
141.9 feet: thence South 77 20'
East 81.8 leet to the Northeast
corner of said lot; thence South
12" 40' West alone the Easterly
line thereof 141.9 feet to the
nnint nf beginning.
Said sale is made pursuant to
an Execution issued out of the
Circuit Court of the State of Ore
gon, for the County of Jackson on
th 23rd dav of ADnl. 19o9. in
matter wherein Charles B. Beck
is Plaintiff and Joseph Ellsworth
Damewood and Edna M. Damewood
aw Defendants.
Dated this 28th dav of April. 1959
-Joseph D. Walsh. Sheriff
Jackson County, Oregon
Portland - Oregon's Centen
nial celebration this summer
'expects to have something for
everybody.
In Portland, the 65 -acre
Centennial Exposition and In
ternational Trade Fair opens
June 10. It will run for 100
days until Sept. 17.
Throughout the state tradi
tional events, such as the
Pendleton Roundup, the Ash
1 a n d Shakespearean festival
and the Portland Rose Festi
val, will be expanded. Hun
dreds of other events are be
ing held in communities for
the first time.
Culture and history are be
ing marked in every county.
The Portland Symphony,
along with othefc musical
No. 10,111'
NOTICE OF HEARING ON
FINAL ACCOUNT
IN THE CIRCUIT COURT OF THE
STATE OF OREGON FOR JACK
.SON COUNTY
PROBATE DEPARTMENT
In the Matter
of
the Estate of Flonnie M. Woold
ririffe. dereased. '
NOTICE IS HEREBY GIVEN that
the undersigned has filed its Final
Account and Report in the above
entitled estate, and that by order
of the Circuit Court in and for
Jackson County, Oregon, Probate
Department, a hearing upon the
same has been set for Monday,
June 22, 1959, in the Circuit Court
Room at the Court House in. Med
ford. Jackson County, Oregon, at
the hour of 9:30 o'clock A.M.
All persons having objections
thereto are hereby notilied to pre
sent the same on or before such
time.
Dated this 14th day of May, 1959
. THE FIRST NATIONAL BANK
OF OREGON, PORTLAND
Executor
Roberts, Kellington & Branchfield
Attorneys for Executor
Exposition, Trade
Fair Scheduled to
Open or June 10
the
remain on display for
balance of the summer.
Culture Achievements
Ghana, for example, will
exhibit its culture achieve
ments at the fair for the first
time in any country. Bulgaria
and Yugoslavia will both have
exhibits, giving the west coast
its first look at the wares of
nations in the Russian orbit.
Another first for the fair
will be the combined exhibits
(in one area) of the European
Community of Nations
France, Great Britain, West
Germany, Italy, Belgium, and
the Netherlands.
Asia will be represented by
Japan, the Philippines, Ma
laya, India and Hong Kong.
The trade fair has invited
groups, will tour the state.
The San Francisco Opera com
pany will perform in Port
land. -
Stale-Wide Contests
State - wide art, sculpture,
poetry, music and literature
contests are being sponsored
by the state. Much of the best
of the states culture will be
on display at the Exposition.
A major feature of the Ex
position, much of which is
being held in an 11-acre build
ing, the second largest in the
world, is the International
Trade Fair, which runs for
two weeks.
The fair has under contract
nearly 30 nations, making it
the largest such fair ever held
on the West coast and the sec
ond largest yet held in Amer
ica. After the trading at the
fair ends, the exhibits will
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19,000 west coast buyers of
foreign products to attend,
hoping that many will con
tinue to import through the
Port of Portland after the
fair ends.
The state has budgeted
$455,000 to underwrite spec
tacular-type shows that will
run nightly at the Exposition
arena, opening June 11 with
the 1959 Ice Capades. This
show will close on June 24.
Other top attractions in
clude Country America, June
26-July 5; Roy Rogers, July
10-16; Harry Belafonte, July
23-25; Art Linkletter, July
26-30; Sam Snyder's Water
Follies, Aug. lr-14; Japanese
Takarazuka Kabuki Revue,
Aug. 24-29; "Oregon Story,"
composed and directed b y
Meredith Willson, Sept. 2-17.
Wayne Dailard, Exposition
executive producer, said he
also expects to sign Lawrence
Welk and Fred Waring.
In addition to hundreds of
commercial exhibits, ranging
from a $160,000 exhibition
home to a vast General Mo
tors exhibit, there will be doz
ens of educational shows.
International Garden
Along with an International
Garden of Tomorrow, contain
ing 5000 of the newest rose
hybrids and thousands of rare
and exotic plants shipped
from around the world, there
will be an atomic energy ex
hibit, a Frontier Village, an
Adventureland and a Gayway
of rides.
Through Adventureland
will be a narrow gauge rail
road, over which will run
three full trains, one a model
of a mid-1 9th century steam
train.
A new expanded-shale wall,
built of blocks designed for
the Centennial, , will enclose
Adventureland. :
The Exposition site is just
across the Interstate Bridge
from Vancouver, Wash., on
Highway 99. Here is enough
parking to handle 17,000 cars,
plus additional space for any
overflow.
Special Trains
Special trains will haul
Centennial visitors free from
the parking area to the Ex'
position, a quarter of a mile
away.
Handling the crowds will
be a police force large enough
for a city of 10,000.. Firemen
will be quartered on the Ex
position grounds for the dur
ation. " ' '
An Aqua Center, across the
street from the Centennial,
will be the scene this summer
of the National Outboard Mo
tor Boat Races. Special sight
seeing trips may be made from
the center and other points.
Watershows are planned on
the week ends. Nearby will
be a Navy exhibit, along with
defense department exhibits
of the latest missiles and oth
er modern weapons.
A huge natural resources
exhibit, showing off all of the
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state's built-in assets, will oc
cupy a wing of the Exposition
hall in a huge panoramic dis
play. ;
Most of the counties in Or
egon, along with the state of
Alaska, are planning displays
to show off special features of
their areas.
Connecting all these points
is a communication system,
large enough to take care of j
the telephone traffic of a city
of 4,000 people. In addition
special microwave towers are
being erected to relay televis
ion shows, such as the Art
Linkletter's Hpuse Party that
will originate, at the Exposi
tion for a week .during the
summer.- .
In order to coordinate all of
the hundreds of events, spec
ial information centers have
been set up around the state
on the main highways enter
ing Oregon.
Oregon expects 6 to 8 mil
lion visitors this summer.
Housing them will be a gigan
tic job. A housing information
center has been set up in Port
land. When hotels, motels and
trailers are filled, some 5,000
private homes will be made
available for the overnight
guests. v
Spend Two Days
It is estimated that an aver
age family will need to spend
more than two days just look
ing at all of the exhibits at
the Exposition and Interna
tional Trade Fair in Portland.
Downstate, each county and
more than 165 cities have
special Centennial committees
who have completed programs
ranging from gold panning
expeditions to rebuilding the
business district as a replica
of the Old West. . A state co
ordinator who handles all of
these activities estimates that
$2 million in directly raised
funds or donations has been
spent on .local celebrations
outside the Exposition in
Portland.
Centennial commission e r s
estimated the Portland Expo
sition value at $20 million, in
cluding the value of the 11-
acre livestock Exposition hall
that was renovated at state
expense and leased from
non-profit group.
History nas not Been ne
glected. Most communities
have marked historical sites
never before posted with
signs. Every classroom is Or
egon - an estimated 18,000 -
received a special Centennial
lesson plan kit to help teach
ers put over the story of the
state. Three special plays
about Oregon's history have
been written and distributed
for classrooms.
Schools Set Up
Schools have been set up by
restaurant owners, motel op
erators, police forces and taxi
firms to teach their employees
more about the , history and
facts of Oregon so they may-
intelligently answer tourist
questions.
Most major magazines have
run special features on either
Oregon history or the Centen
nial. Thousands of stories
have been published by the
nation's leading newspapers.
Special radio programs have
gone out over the country's
networks. Outdoor advertis
ing has been used extensively.
The latest publicity stunt is
the trek of a wagon train
that began a 100-day journey
from Independence, Mo., his
toric starting place of the
Oregon Trail, to Indepen
dence, Ore.
Advertising Budget
Overlaying all the public
ity, is a quarter of a million
dollar Centennial advertising
budget for ads in national
publications. This is in addi
tion to advertising done by
the State highway department
and private firms.
All this effort has not come
easily. Oregon had no one
with experience in putting on
a- Centennial. Persons were
hired from other areas who
had taken part in various ex
positions and trade fairs.
As in all such undertakings,
there have been disputes, dis
agreements and shifting of
personnel. But now the big
jobs are done. All that re
mains are hundreds of details,
being handled on a daily basis
by a management committee
of the Centennial commission
and by a staff of some 507
employed Centennial workers
and planners. "(John Snider,
Medford mayor and a com
missioner, is a member of the
management committee.) '
Construction phase of the
Exposition, now running
ahead of schedule, will finish
by May 15, when exhibitors
will start moving in displays
already designed and a build
ing for erection at the Ex
position. A huge mural, covering
some 500 feet of the face of
the Centennial building, will
be erected June 1. It, along
with five major sculpture
.pieces, is being done by pro
I fessiona) artist under direc
tion . of architects who have
planned the Centennial lay
out. The commission has let con
tracts for concessions with an
eye toward holding down
prices. Also special effort is
being made to provide rest
areas for the Exposition
vistors.
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Why is the printed word
-
so important in advertising?
ONE OF A
SERIES
ANSWER: THE DAILY NEWSPAPER IS THE GREAT
EST ADVERTISING MEDIUM for many reasons. One
of them is that it carries the power of the printed word.
People believe in a message that is permanent; one that is
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MEDFORD MAIL TRIBUNE