Vitamin 6-6 Found
To Be Helpful in
Inborn Error Case
IP
By DELOS SMITH
UPI Science Editor
New York-l?I-An exceed
ingly rare child has provided
science with some much-
' needed insight
into the mys
teries ol hu
man brain
c h e m istry -much
needed
because errors
in that chem
istry may well
mit'- Aot both men-
tal deficiency
and of schizophronia, the men
tal disease which puts more
victims into mental hospitals
than all others combined.
This child, who now is six
years old, has an inborn error
in her brain chemistry. Four
hours after birth she went
into convulsions. The drugs
which usually stop convul
sions didn't stop hers, but
they were stopped when one
of the more obscure vitamins,
vitamin B-6 or pyridoxine,
was injected into her body.
Dependent Upon Vitamin B-6
Since she was two years old
she has had no convulsions
only because she has been
given a relatively large dose
of vitamin B-6 daily. She is
wholly dependent upon an
outside supply of the vitamin
which makes her a rare hu
man being. The chemistry of
practically all people has no
trouble extracting vitamin
B-6 from food or if the diet
contains none, in making it.
Aside from this in -born
error and a decided mental
deficiency, the child seems to
be entirely normal physically.
Whether the mental defic
iency and the in-born error
are connected, no one can
say. The present state of
knowledge of human brain
chemistry leaves much to be
desired. For that reason, this
child's case is of prime scien
tific interest.-
Five scientists of the Na
tional Institutes of Health,
Bethesda, Md., withheld vita
min B-6 from the little girl.
Within 72 hours she began
going into convulsions. These
convulsions were stopped
promptly by injections of the
vitamin. Chemical measure
ments were made before, dur
ing, and after the convulsions.
The measurements were of
blood flow through the brain;
of the rate at which the brain
tissue utilized the oxygen
brought to it by the blood; of
the differences between the
oxygen in the blood entering
the brain and the blood leav
ing the brain; of the ratio of
use the brain tissue gets from
the breathing in and out of
air, to total body utilization.
Provided Insight
There were marked differ
ences in all these measure
ments during convulsions and
before and after. But all but
cne were within the limit of
MedfGrd
Tribune
2nd SECTION
"MEDFORD, OREGON, THURSDAY, APRIL 16, 1959
12 Pages
Ashland Groups Help Launch Drive
To Raise Funds For High School Band
Ashland Seeking to under
write the cost of sending the
Ashland High school band to
the Portland Rose Festival,
several local civic groups have
joined forces to launch a
"Rogue to Roses" money-seeking
effort. ,
Climax of the campaign will
be a varied benefit entertain
ment Saturday, April 18, at
deviations to be expected
among people and the scien
tists said it "was difficult to
draw conclusions from them."
However, the one which was
outside these limits, provided
the much-needed insight.
That measurement showed
a marked increase in the
cerebral utilization of oxygen
during seizure. Oxygen is the
basis of energy and the added
energy had no place to go
except into convulsions. The
scientists reasoned that vita
min B-6 controlled"the chemi
cal background of the brain
which if it had been whole,
would have governed as it
does in normal brain chem
istry. The scientists in this team
accomplishment were Louis
Sokoloff, Niels A. Lassen,
Guy M. McKhann, Donald B.
Tower, and Wayne Albers.
Southern Oregon college.
Total amount needed for
the tour is $2,410, but the
band has raised $300 and
pledged an additional $250,
lowering the goal of the cur
rent ticket sale to $1,860. The
sum will finance the appear
ance of the band, five major
ettes, and five flag girls in
the Junior Rose Parade and
the Grand Floral Parade, and
will also make it possible for
an Oregon Shakespearean Fes
tival float to accompany the
group in both parades.
Feature Performance
Saturday night's benefit
will feature a performance of
the melodrama, "He Ain't
Done Right By Our Nell,"
staged by the SOC Players
under the direction of Dorothy
Stolp. Audience members will
be encouraged to cheer the
hero and hiss the villain.
Oleo acts, composed of can
can girls and a male quartet,
will precede and follow each
production of the melodrama,
set forstwo showings at 7:30
and 9:30 pjn. in Churchill hall
auditorium.
Immediately after the first
staging of the play, Ashland
High school's dance band will
provide music for a dance and
box social arranged for a 9:30
pjn. start in tne uritt center
ballroom. As traditionally,
participants will vie for the
ladies' . attentions by bidding
on the box lunches. Special
prizes have also been arranged
for, winning bidders.
Tickets Available
Tickets may be obtained
from members of the Rotary
club, high school students, at
the Ashland Chamber of Com
merce, or from any member
of the Band Boosters club.
Those who plan to bid on the
box lunches are asked to bring
a box lunch to place on the
auction block.
For the benefit of school
children, a special matinee
performance of the melodrama
will be given Saturday at 2:30
p.m.
Both the band and the
Shakespearean Festival float
will promote the attractions
of Ashland and the Rogue
valley. Since thousands of ad
ditional Centennial visitors
are expected to launch their
Oregon trip at the Portland
Rose Festival, spokesman for
the Ashland campaign indicate
that an appearance by a local
group would be of key im
portance in attracting - new
tourist visitors to southern
Oregon.
Connie Nicholas
Declared Guilty
Indianapolis, Ind. -(UPD- An
all -husband jury today con
victed Mrs. Connie Nicholas
o f voluntary manslaughter
for killing business executive
Forrest Teel, her married
lover of 15 years.
The verdict carried auto
matic punishment of two to
21 years in prison. The tiny
divorcee will be eligible
for a parole hearing in
21 months. Voluntary man
slaughter is defined in Indi
ana as a slaying in passion,
but" without malice or pre
meditation. The verdict was the lighest
she could have got without
acquittal.
WaDD Street Chatter
New York - (DPB - Walston
& Company notes April 16
was the last day of the big
income tax "bite" and says
possibly the easing of this
pressure of selling to raise
tax money may put some
"spring" in the spring rally.
, International Statistical Bu
reau says there is evidence of
increased buying of non-taxable
bonds and slightly more
interest in other bonds with
a high yield, suggesting that
the low in bond prices may
have been seen, or at least
that not much further decline
is likely.
Alexander Hamilton Insti
tute urges that fresh commit
ments be confined to securi
ties of good quality with. ris
ing earnings rather than the
glamour or highly speculative
types in view of the numer
ous important problems
which still remain to be solv
ed, including wage negotia
tions in steel and other lead
ing industries, clarification of
the Near East oil situation
and the coming conference in
Geneva.
The Spear and Staff mining
and metal stock letter says
Hudson Bay, American Metal
Climax, Island Creek Coal,
New Jersey Zinc, Eagle Pich
er, Pittston, U. S. Smelting
and South American Gold
and Platinum have ben un
der selling pressure and could
become "sales" for traders if
the support zones under their
current prices levels are vio
lated by a significant margin.
W. T. "Bill" Fasel
REALTOR
Phone SP 3-3517
1244 S. Riverside
In 1824, the Marquis de La
fayette, then 67, visited each
of the 24 states.
iwstaMry
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its mgH
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132 West Main Street
21 South Central
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