East Oregonian : E.O. (Pendleton, OR) 1888-current, November 26, 2016, WEEKEND EDITION, Page Page 2A, Image 2

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    WEATHER
East Oregonian
Page 2A
REGIONAL CITIES
Forecast
SUNDAY
TODAY
MONDAY
Considerable
cloudiness
A couple of
afternoon showers
53° 36°
46° 38°
TUESDAY
Mostly cloudy, a
shower; breezy
Today
WEDNESDAY
Astoria
Baker City
Bend
Brookings
Burns
Enterprise
Eugene
Heppner
Hermiston
John Day
Klamath Falls
La Grande
Meacham
Medford
Newport
North Bend
Ontario
Pasco
Pendleton
Portland
Redmond
Salem
Spokane
Ukiah
Vancouver
Walla Walla
Yakima
Sun and clouds
with a shower
Some sun, then
turning cloudy
PENDLETON TEMPERATURE FORECAST
47° 34°
45° 35°
46° 31°
HERMISTON TEMPERATURE FORECAST
49° 41°
54° 36°
PENDLETON
through 3 p.m. yesterday
TEMPERATURE
HIGH
LOW
54°
44°
66° (1894)
46°
30°
2° (1993)
PRECIPITATION
24 hours ending 3 p.m.
Month to date
Normal month to date
Year to date
Last year to date
Normal year to date
Trace
0.78"
1.20"
11.17"
7.81"
11.23"
HERMISTON
through 3 p.m. yesterday
LOW
58°
46°
70° (1960)
SUN AND MOON
Dec 7
Full
7:10 a.m.
4:15 p.m.
4:12 a.m.
3:14 p.m.
Last
Dec 13
Dec 20
Beijing
Hong Kong
Jerusalem
London
Mexico City
Moscow
Paris
Rome
Seoul
Sydney
Tokyo
W
r
c
sn
r
c
c
r
c
c
c
sn
c
c
r
r
r
pc
c
c
r
c
r
c
c
r
c
r
Hi
53
42
40
51
38
39
50
45
49
41
41
43
40
49
53
54
48
51
46
49
45
51
41
40
49
48
50
Lo
48
28
33
44
28
32
44
36
41
37
31
37
35
41
46
45
30
38
38
46
34
44
33
33
46
36
34
Shown are noon positions of weather systems and precipitation. Temperature bands are highs for the day.
W
r
c
pc
r
pc
c
c
sh
pc
c
pc
c
r
r
r
r
pc
pc
sh
sh
pc
pc
pc
sf
sh
pc
pc
Hi
48
68
57
49
67
32
50
63
40
78
54
Lo
26
58
39
40
43
29
39
43
33
66
47
Sun.
W
s
r
s
pc
pc
sn
c
pc
r
pc
pc
Hi
44
68
59
47
74
36
47
61
48
73
53
Lo
21
59
43
38
42
28
36
43
26
67
50
W
s
sh
s
pc
pc
sn
c
pc
pc
pc
r
WINDS
Medford
50/38
Trace
0.52"
0.98"
7.85"
5.39"
8.29"
Lo
42
27
27
42
26
30
39
33
36
33
26
36
33
38
42
43
31
34
36
41
26
40
34
29
41
36
30
Today
Caldwell
53/34
Burns
45/26
PRECIPITATION
Nov 29
Bend
44/27
Hi
52
46
44
51
45
47
49
51
54
51
42
51
50
50
50
52
52
55
53
49
49
49
48
47
49
53
50
NATIONAL WEATHER TODAY
Sun.
WORLD CITIES
John Day
51/33
Ontario
52/31
46°
31°
-4° (1985)
24 hours ending 3 p.m.
Month to date
Normal month to date
Year to date
Last year to date
Normal year to date
Sunrise today
Sunset tonight
Moonrise today
Moonset today
New
First
Albany
49/42
Eugene
49/39
TEMPERATURE
Yesterday
Normals
Records
50° 32°
Spokane
Wenatchee
48/34
48/33
Tacoma
Moses
50/37
Lake
Pullman
Aberdeen Olympia
Yakima 49/31
49/35
49/38
50/37
50/30
Longview
Kennewick Walla Walla
50/41
53/36 Lewiston
56/35
Astoria
51/36
52/42
Portland
Enterprise
Hermiston
49/41
Pendleton 47/30
The Dalles 54/36
53/36
51/35
La Grande
Salem
51/36
49/40
Corvallis
49/41
HIGH
50° 35°
Seattle
51/41
ALMANAC
Yesterday
Normals
Records
53° 34°
Saturday, November 26, 2016
(in mph)
Boardman
Pendleton
Klamath Falls
42/26
Sunday
WSW 7-14
WSW 7-14
UV INDEX TODAY
Shown is today’s weather. Temperatures are today’s highs and tonight’s lows.
REGIONAL FORECAST
Coastal Oregon: Occasional rain today into
tomorrow. Monday: mostly cloudy with a
shower.
Eastern and Central Oregon: Showers of
rain and snow near the Cascades today.
Some sun, then clouds in the east.
Western Washington: Rain today, steadiest
and heavies his morning. A couple of show-
ers this evening.
Today
SW 6-12
SW 6-12
Eastern Washington: Showers around
today; a bit of morning snow, then a little
rain toward the Cascades.
Cascades: Mostly cloudy today with rain
and snow; snow level mostly near 4,000 feet
with 3-6 inches.
Northern California: Rain today, but snow
snow in the interior mountains with slower
and diffi culr travel.
0
1
1
1
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0-2, Low
3-5, Moderate 6-7, High;
8-10, Very High;
11+, Extreme
The higher the AccuWeather.com UV Index™ num-
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-10s
-0s
showers t-storms
0s
10s
rain
20s
flurries
30s
40s
snow
ice
50s
60s
cold front
70s
80s
90s
100s
warm front stationary front
110s
high
low
National Summary: Snow showers will extend from the Great Lakes to northern New
England and the central Appalachians today. Rain and mountain snow will push southward
on the Pacific coast. Most other areas will be dry.
Yesterday’s National Extremes: (for the 48 contiguous states)
High 87° in Edinburg, Texas
Low 0° in Leadville, Colo.
NATIONAL CITIES
Today
Albuquerque
Atlanta
Atlantic City
Baltimore
Billings
Birmingham
Boise
Boston
Charleston, SC
Charleston, WV
Chicago
Cleveland
Dallas
Denver
Detroit
El Paso
Fairbanks
Fargo
Honolulu
Houston
Indianapolis
Jacksonville
Kansas City
Las Vegas
Little Rock
Los Angeles
Hi
55
64
55
55
51
62
53
47
69
47
48
45
66
60
46
67
0
44
84
72
49
72
58
64
58
64
Lo
41
36
40
34
31
31
33
35
38
29
33
34
53
35
31
53
-4
26
71
52
32
46
43
47
35
50
W
c
s
pc
pc
pc
s
c
r
pc
pc
pc
sn
pc
s
pc
c
c
s
pc
s
pc
pc
s
s
s
r
Sun.
Hi
51
65
51
52
48
67
47
45
64
54
50
51
71
55
49
67
2
44
84
76
52
70
58
57
59
61
Lo
33
46
37
30
29
49
32
33
40
31
40
35
62
28
35
43
-3
36
72
66
41
49
49
39
50
48
Today
W
pc
pc
s
s
c
pc
c
c
s
pc
pc
pc
c
c
pc
s
c
pc
pc
pc
s
s
sh
pc
c
c
Louisville
Memphis
Miami
Milwaukee
Minneapolis
Nashville
New Orleans
New York City
Oklahoma City
Omaha
Philadelphia
Phoenix
Portland, ME
Providence
Raleigh
Rapid City
Reno
Sacramento
St. Louis
Salt Lake City
San Diego
San Francisco
Seattle
Tucson
Washington, DC
Wichita
Hi
54
58
82
49
44
55
67
53
63
57
54
76
48
50
60
56
52
55
57
54
65
57
51
80
56
61
Lo
31
34
66
33
29
28
46
38
47
34
38
52
32
34
31
28
36
43
38
36
56
49
41
49
38
45
W
pc
pc
pc
pc
pc
pc
s
pc
pc
pc
pc
c
c
pc
s
pc
c
r
s
c
c
r
r
c
s
s
Sun.
Hi
58
61
80
50
46
62
69
47
65
56
50
63
43
47
59
51
44
58
55
45
66
59
49
64
55
64
Lo
43
51
69
41
41
45
57
35
50
40
34
45
29
30
34
29
31
44
46
31
51
51
42
43
36
43
W
s
pc
pc
pc
r
pc
s
pc
c
r
s
pc
c
c
s
c
c
pc
pc
sf
sh
pc
sh
pc
s
sh
Weather (W): s-sunny, pc-partly cloudy, c-cloudy, sh-showers, t-thunderstorms, r-rain,
sf-snow flurries, sn-snow, i-ice.
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COMMERCIAL PRINTING
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Team of deaf scientists probe hearing loss treatments
LYNNE TERRY
The Oregonian/OregonLive
PORTLAND — When Peter
Steyger learned to speak, he had to
wear hearing aids.
At 14 months, he was struck with
meningitis. The powerful antibiotic
that saved his life largely stripped
him of hearing.
His mother, determined to keep
him in the hearing community,
worked with him an hour a day for
four years as part of an intensive
regime of speech therapy. Some-
times it took him 10 minutes to
learn a single word. He didn’t start
to catch up to his peers until eight
years later.
But today at 54, Steyger is a
prominent auditory neuroscientist.
At Oregon Health & Science
University, he’s part of a team of
researchers who are studying the
auditory system in hopes of helping
others who can’t hear.
The 10 faculty members in
OHSU’s Oregon Hearing Research
Center are considered trailblazers
among their peers.
“I look at their program as a very
unique one in the world because
of the breadth and the depth of
their auditory science and the high
quality of the science that’s done
there,” said Jennifer Stone, an audi-
tory neuroscientist at the University
of Washington in Seattle.
The center also stands out in
another way: It has five professors
with hearing loss. Few other audi-
tory research departments have
even one scientist with a hearing
disability. None has as many as
OHSU, experts say.
Their varied biomedical back-
grounds allow them to study every
aspect of the auditory system, and
their personal experiences inform
their research.
“They’ve all got pretty high
profiles and are covering lots of
different bases,” said Jonathan
Ashmore, a leading auditory
neuroscientist based at University
College London in Britain.
Their work has helped make the
center, dating to 1967, one of the
biggest nationwide. About a dozen
other universities have hearing
research centers with at least three
faculty members. Only about five
have 10 or more. OHSU’s depart-
ment of otolaryngology — an ear,
nose and throat specialty — is No.
2 in funding from the National
Institutes of Health, at $10 million
a year, right behind Johns Hopkins
University.
For the scientists, it’s not been
easy. Their hearing loss has compli-
cated their lives. They struggled to
follow their teachers and profes-
sors, keep up in graduate school
and complete their post-doctoral
training. They had difficulty taking
notes. They suffered from a sense of
isolation and found it tough to make
friends.
But they found a home at the
Oregon Hearing Research Center.
They’re not alone in their disability,
and they have a personal motivation
to succeed. Though their research
might not cure their own hearing
loss, they hope to help the hearing
of future generations.
“Each and every one of them
Corrections
The East Oregonian works hard to be accurate and
sincerely regrets any errors. If you notice a mistake in
the paper, please call 541-966-0818.
had to work very hard to overcome
the disabilities that they have but
they’re all extremely effective
communicators and very effective
teachers,” Stone said. “Each and
every one of them is a leader in their
field.”
Steyger’s specialty is the toxicity
of certain pharmaceutical drugs
to the inner ear. He’s studying a
powerful class of antibiotics called
aminoglycosides, which are known
to damage hearing.
Unlike some other antibiotics
such as penicillin, which prevent
bacteria from dividing, aminogly-
cosides kill bacteria. They include
Gentamicin and Streptomycin,
which Steyger was given for
meningitis. He figures the antibiotic
was responsible for his hearing loss
or contributed to it.
His Ph.D. thesis at Keele
University in England, where he
was born, focused on aminoglyco-
side-induced damage to the inner
ear, which governs hearing and
balance. In post-doctorate work at
Keele, he studied the anatomy and
function of the cochlea — part of
the inner ear. When he got an offer
from OHSU in 1997, he set up shop
on the hill.
His lab is trying to understand
how aminoglycosides cross the
blood-labyrinth barrier, which has a
similar function to the blood-brain
barrier but instead of protecting
the brain, it protects the ears from
harmful substances. Aminoglyco-
sides exploit an existing pathway
for other compounds, allowing
them to barge through the physical
barrier.
Both infections and amino-
glycosides can harm hearing by
themselves, and in a triple whammy
effect, the inflammation that’s
caused by an infection allows more
of the antibiotics into the inner ear.
Steyger is trying to understand the
mechanics of how that happens.
“This is a serious issue, and it’s
not just affecting me,” he said. “It’s
still affecting people today.”
Eighty percent of premature
babies who enter a neonatal inten-
sive care units get antibiotics to
prevent infections, Steyger said. If
they’re kept on them long enough,
they can lose their hearing.
“When a kid is born, if they’re
not treated with aminoglycosides
and they have an infection, they can
die within 12 hours,” Steyger said.
“That’s why so many kids will get
the drug.”
His choice to focus on hearing
was strategic, he said.
“I expected that they would be
more welcoming of a hearing-im-
paired person,” said Brigande,
51. “The annual meetings would
have captioning. They would have
listening technologies. I thought
that this would be an obvious, clear
path to give me the best chance to
communicate effectively.”
At OHSU, he’s working with
mice that are congenitally deaf.
He’s found a way to introduce a
healthy gene into the inner ear
while the animal is in the womb.
When they’re born, they can hear.
“John’s a superstar,” Ashmore
said. “That really is a technical
discovery of the first order.”
Brigande wants to see his work
benefit people.
“I’m passionately committed
to trying to make that happen,”
Brigande said. “I would love to be
able to spare a child from growing
up with hearing loss.”
Besides breaking new ground in
the lab, Brigande has raised aware-
ness about the need to accommodate
students with hearing impairments
on the campus. Together with
Steyger, he’s persuaded OHSU
management to equip conference
halls with assisted-listening devices.
The center’s director, Alfred
Nuttall, 73, whose hearing loss
started in his 40s, said their personal
situations didn’t influence the
decision to hire Steyger, Brigande
and Lina Reiss, who’s 41 and
another member of the department
with severe hearing loss. Frederick
Gallun, 45, originally hired by the
VA Portland Health Care System,
also conducts auditory research at
the center and can hear out of only
one ear.
Another researcher at the center,
John Brigande, is focused on
preventing deafness through treat-
ments in the womb.
Like Steyger, Brigande has
profound hearing loss. He gradu-
ally lost hearing in his left ear from
some unknown cause. By the time
he was in college, he had to wear
hearing aids. But having them all
has turned out to be an advantage
for the scientists. It creates camara-
derie and boosts their confidence in
their work.
“It’s very stimulating to be
around a group with many deaf
people,” Reiss said.
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