* * / • • ■ V ? » !•* ¿ ’‘. y f < S i > Æ 7 ^ . ? y r ? .¡^»** *•'**•• . ’.■ Æ g .--,. P age B2 M arch 12, 1997 • T he P or i la n d O bserve Don’t worry: a brain still can’t be cloned Explorers returning from distant lands tell o f aborigines so afraid o f cameras that they recoil from the sight o f a lens as i f they were look ing down the barrel o f a gun. Taking their picture, they fear, is the same as stealing their soul. You might as well just shoot them dead on the spot. Knowing that a photograph is only skin deep, people in the developed lands find such terror absurd. But the fear that one’s very identity might be stolen, that one could cease to be an indi vidual, runs deep even in places where cameras seem benign. The queasiness many people feel over the news last week that a scien tist in Scotland has made a carbon copy o f a sheep comes down to this, if a cell can be taken from a human being and used to create a geneti cally identical double, then any o f us could lose our uniqueness. O ne would no longer be a self. There are plenty o f other rea sons to worry about this new divide the biologists have trampled across. Nightmare o f the week goes to those who imagine docile flocks o f en- slaved clones raised for body parts. But the most fundamental fear is that the soul will be taken by this penetrating new photography called cloning And here, at least, the no tion is just as superstitious as the aborigines’. There is one part o f life biotechnology will never touch. While it is possible to clone a body, it is impossible to clone a brain. That each cceature from microbe to man is unique in all the world is amazing when you consider that every life form is assembled from the same identical building blocks. Every electron in the universe is indistinguishable, by definition. You can’t tell one from the other by exam in in g it for nicks and scratches All protons and all neu trons are also precisely the same. And when you put these three kinds o f particles together to make atoms, there is still no individuality. Every carbon atom and every hydro gen atom is the same. When atoms are strung together into complex mol ecules — the enzymes and other pro teins — this uniformity begins to break down Minor variations occur. But it is at the next step up the ladder that something strange and wonderful happens. There are so many ways molecules can be com bined into the complex little ma chines called cells that no two o f them can be exactly alike. Even cloned cells, with identi cal sets o f genes, vary somewhat in shape or coloration. The variations are so subtle they can usually be ignored. But when cells are com bined to form organisms, the differ ences becom e overw helm ing. A threshold is crossed and individual ity is born. Two genetically identical twins insidea womb will unfold in slightly different ways. The shape o f the kidneys or the curve o f the skull w on’t be quite the same. The differ ences are small enough that an or gan from one twin can probably be transplanted into the other. But with the organs called brains the differ ences become profound. All a body’s tissues - bone, skin, muscle, and so forth — are made by taking the same kind o f cell and repeating it over and over again. But with brain tissue there is no such monotony. The precise layout o f the cells, which neuron is connected to which, makes all the difference Linked one with the other, through the junc tions called synapses, neurons form the whorls o f circuitry whose twists and turns make us who we are. In the reigning metaphor, the genome, the coils o f DNA that carry the genetic inform ation, can be thought ofas a computer directing the assemblyoftheembryo Back-of-the- envelope calculations show how much information a human genome con tains and how much information is required to specify the trillions of connections in a single brain. I he conclusion is inescapable: the problem o f wiring up a brain is so complex that it is beyond the power ot the genomic computer. The best the genes can do is indi cate the rough layout of the wiring, the general shape o f the brain. Neu rons, in this early stage, are thrown together more or less at random and then left to their own devices. After birth, experience makes Tricked On To Heroin and breaks connections, pruning the Once the twins left the room, the thicket into precise circuitry. From differences between them would in the very beginning, w hat’s in the crease genes is different from w hat’s in the Send one twin around the block brain. And the gu lf continues to clockwise and the other counter widen as the brain matures clockwise and they would return with The genes still exert their influ more divergent brains. For artificial ence — some o f the brain’s circuitry clones the variations would accu is hardwired from the start and im mulate even faster, for they wou Id be mutable People don’t have to learn born years apart, into different to want food or sex. But as the new worlds. connections form, the mind floating Photography is only skin deep. higher and higher above the genetic Cloning is only gene deep. But what machinery like a helium balloon, about the ultimate cloning — copy people learn to circumvent the baser ing synapse by synapse a human instincts in individual ways. brain? Even genetically identical twins, If such a technological feat were natural clones, are born with differ ever possible, for one brief instant ent neural tangles. Subtle variations we might have two identical minds. in the way the connections were But then su p p o se neu ro n No. originally slapped together might 20478288 were to fire randomly in make one twin particularly fasci brain I and not in brain 2. The tiny nated by twinkling lights, the other spasm would set off a cascade that drawn to certain patterns o f sounds reshaped some circuitry, and there Even if the twins were kept in would be two individuals again. the same room for days, these natu We each carry in our heads com ral predilections would drive them plexity beyond imagining and be each in different directions. Experi yond duplication. Even a hard-core ence, pouring in through the senses, materialist might agree that, in that would cause unique circuitry to form sense, everyone has a soul. i s M Americans are turning to heroin drink alcohol and smoke pot on a after having become addicted. greater profits. in alarming numbers all due to some pretty regular basis. After a while You may have noticed an inter The quickest and most dangerous very brilliant marketing strategies the high I got from marijuana w asn’t esting pattern o f use in Eric. The drug route is injecting a drug in a o f the drug cartels. What is this enough and I started taking LSD back and forth that can often be seen blood vessel as the results are in strategy? Get heroin on to the streets and eventually cocaine. The cocaine in the use o f stimulant and sedative stant. Once an overdose, too much o f in concentrations strong enough to began to make me very jittery and type drugs, following addiction to a drug, is injected, there is rarely any snort (sniff) or smoke so that inject paranoid and this bothered me. My the gateway drugs. For example, the turning back. The effects o f smok ing heroin is not necessary to expe cocaine connection also sold heroin stimulation o f methamphetamines ing a drug also occurs very rapidly rience its alluring effects. Street and asked me if I wanted to try it. At is solved by sedation with alcohol, through absorption o f the drug via heroin has become available in much first I said "no”, but a couple o f days GHB, Rohypnol, and other downers. the lungtissuedirectly into the blood stronger concentrations o f 60 to 70 later I tried heroin for the first time Stimulation with cocaine and then stream, bypassing the digestive sys percent pure or higher, making the by sniffing it. This was the begin sedation with heroin. Or stimula tem altogether. While the majority snorting and smoking of heroin pos ning o f the end for me. I got so high tion with LSD, ecstasy or herbal o f the drug-using population is not sible. the first time I did it I vomited for a ecstasy, and sedation with alcohol, willing to use drugs intravenously, In the past heroin was diluted to couple o f hours and passed out. I heroin or other sedative. This use o f they are willing to smoke or snort a as little as 5% o f less for the purpose H o no rs loved how it made me feel so I did it A N D uppers then downers can often be drug. In the case o f heroin, they o f increasing the profits made by again, and again, and again. Before combined, sometimes with deadly N C O U R A G E S D iv e r s i T Y usually begin to inject the drug once drug dealers and heroin was almost I knew it I was spending about $ 100 results Remember the famous ex addiction occurs. always used intravenously. Smok a day sniffing heroin. ample ot "speedball” use (heroin Even though "crack” or “ ice," ing or snorting heroin was not very ‘I told m yselfl would never shoot K aiser P erm a n e n te is e n ric h e d by the c o n trib u tio n s of and cocaine injected at the same and “Persian heroin” are just differ effective and rarely done, as the drug (inject) heroin because I didn’t like time) by John Belushi that killed ent forms o f cocaine, metham phet issoexpensive. With today’s heroin, individuals from a wide variety of backgrounds. We’re enhancing our needles. My fear soon gave way be him. This may have been behind the amines and heroin, the effects o f smoking and snorting it has become cause I w asn’t getting as high snort death o f River Phoenix too. workforce to better reflect the people we serve. these drugs when smoked are som e popular and even chic in the club ing heroin. The first time I popped The ingestion o f drugs takes place what different. scene. (injected) two packets I went out for in several ways. There is the drink Apply at our Employement Office, 500 NE Multnomah St., (use first The coating o f poisonous drugs We are now seeing the social bar about ten minutes. I woke up with ing or swallowing o f liquids, pow on the delicate tissues o f the lungs riers o f the user o f heroin come my friend giving me mouth to mouth Floor, Grand Avenue entrance) Portland, OR 97232. Or, call (503) 813-4700. ders. and pills. There is the.snifflng cannot be positive. How much dam down, even though there is no drug resuscitation and a bunch o f girls I of powders and vapors, as in the case age occurs is not fully known. You with a more sinister reputation than Before being considered as an applicant, candidates are required to knew were around me crying. At o f inhalants such as glue, paint, are also at greater risk o f overdosing heroin. Youth are more willing to first I didn t know what was going paint thinner, gasoline, and other complete an on-line application. On-line apps accepted M-F, 8a - 3:30p. from smoking these three drugs. snort or smoke this drug. on but when my friends told me I had industrial poisons. Drugs can be in Only injecting them would be more In the United States there are an turned blue and w asn’t breathing, I jected under the skin or into blood dangerous. estimated 600,000 heroin addicts realized that I was dead and had vessels. Smoking o f tobacco and There is also now ample evidence with the Drug Enforcement Agency been revived! marijuana has long been done. There KAISER PERMAMENTE that drugs and other toxins can re- (DEA) estimating that 2.3 million “ Even after my near death experi are even pharmaceutical drugs ad sidually store in the fatty tissue o f An Equal Opportunity Employer Americans over 12 have used heroin ence I still used heroin and didn’t ministered as enemas; and some the body for long periods in the U.S. With the social barrier o f care. I made me feel so good that I drugs can be absorbed through the o f time. The smoking o f having to inject heroin avoided, we didn’t give a @#$* !#A% about any skin such as LSD and nicotine the oil forms o f these are seeing people more willing to try thing, except that needle. A fter shoot patches. drugs are cause for con heroin by snorting or smoking the ing heroin for a year straight and What became popular in the 1980s cern that more o f the drug drug. O f course, as they become being sick a bunch o f times I decided was the smoking o f drugs that were will remain locked in the addicted to heroin, guess what hap to get some help. I tried methadone not being smoked before. The smok fatty tissue. Narconon pens? You guessed it. They begin to but it made me feel worse and I quit ing o f heroin (chasing the dragon), utilizes a very unique inject the drug as the preferred and went back to heroin. Eventu the smoking o f cocaine (crack), and sauna sweat-out detoxi method o f use! ally, I heard about Narconon and I the smoking o f methamphetamines fication program devel Take the story o f Eric T. and what went to them for help. At first I had (ice). All three forms o f these drugs oped by author and phi happened to him. Eric is now get a hard time, but I now know that I needed to be in much purer concen losopherL. Ron Hubbard ting help at Narconon Ch i Iocco New have the power to be happy and trations for smoking to be effective. to sweat these drug resi Life Center in Oklahoma, but before drug-free." I his holds true for snorting ofheroin dues out o f the body with Eric arrived at Narconon, he had Eric became a heroin addict with as well. Knowing this, the drug car tremendous results. become addicted to heroin. out having to use a needle. He later tels responded, predicting larger As for today’s heroin, “When I was sixteen I started to succumbed to using the needle only number o f consumers would mean the ploy o f putting high potency heroin on the streets is a trick. There is The Pacific University College o f Optometry is pleased to announce the no other way to put it. opening o f its Northeast Eye Center, conveniently located in Northeast Portland Heroin is heroin, and at the Multnomah County Health Center—corner o f MLK Jr Blvd. and Killingsworth. Pacific University faculty and staff offer a hill range o f affordable no matter how you con state-of-the-art vision services provided in a caring and compassionate manner sume it the danger o f addiction looms closely. EYE CARE SERVICES INCLUDE: U.S. Senator Ron Wyden (D What we almost always I Examinations for eyeglasses and contact lenses Wyden said the grant, which was A dm inistration," said W yden. O regon) today announced that see with the advent o f I Care for those with diabetes and high blood pressure awarded to Multnomah County by I he Ryan White Act was autho I Treatment o f eye injuries and diseases such as glaucoma Multnomah County will receive addiction through the the U.S. Department of Health and rized during W yden’s tenure on I Excellent selection o f frames and sunglasses $1.9 million in federal assistance sniffing or smoking o f Human Services’ (HHS) is being the House Commerce Committee. I Free vision screenings for children and adults heroin is a shift to inject to help deliver and enhance HIV- used to provide medical assistance Since then. Wyden has been dogged I Examination o f children with reading problems related outpatient, am bulatory ing the drug. The trick is for those with AIDS or those who in his attempts to obtain funding h e a lth and su p p o rt se rv ic e s complete! Some sight-threatening conditions—such as diabetes and high blood pressure- arc HIV-positive for the growing number of Ameri throughout the county. The money N a rc o n o n In te rn a are common in African Americans, Hispanics and other minority populations. “T his grant provides federal cans who are infected with this Therefore early detection and continued monitoring are important to insure tional is a network o f was awarded to the Multnomah funding for home and com m unity- terrible disease. good vision and eye health. County Health Department as part substance abuse program based care, continuity o f health Wyden also said. "I will work of the Ryan White Comprehensive and treatm ent centers To schedule an appointment or free screening and for more information about insurance coverage and paym ent hard to make sure we continue to AIDS Resources Emergency Act located around the world. vision care services, please call 248-3821. for p h a rm a c e u tic a ls . T o d a y ’s fund community-based AIDS pro which Wyden championed when For more information on award show s a continuing co m grams so that HIV-positive Orego Northeast Eye Center, Multnomah County Northeast Health Center he served in the U.S. House of N arconon services or m itm e n t to c o m m u n ity -b a s e d nians have access to necessary K irxc f.__i:___ -C , . . Representatives help call I (800) 468- 5329 N.E. MLK Jr. Blvd., Portland 6933. ANNOUNCING THE Northeast Eye Center A Clinical Care and Teaching Affiliate o f the Pacific University College o f Optometry Wyden announces Multnomah AIDS/HIV grant (C o m er o f N.E. MLK a n d Killingsworth) 248-3821 V