__Health News _
Drug cocktails help suppress HIV
As of June 1997:
■ The World Health Organiza
tion estimates that there are
30.6 million children and adults
infected with HIV or AIDS
worldwide.
■ The Centers for Disease Con
trol and Prevention report that
there are 612,078 children and
adults infected with HIV or AIDS
in the U.S.
■ Of the 612,078 reported cas
es, 4,021 are in Oregon.
■ Of the 612,078 reported cas
es, 379,258 have died.
SOURCE: CDCWeb page
tained suppression of the virus.
This refutes earlier studies that
have shown that these combina
tion therapies only result in tem
porary suppression of the virus.
HTV and AIDS are viewed as
two points on a continuum. Effec
tive treatment, such as combina
tion therapies, can begin as early
as infection is detected, according
to an April 1997 JAMA editorial.
Combination therapies have
been effective. The Centers for Dis
ease Control and Prevention re
ported a 13 percent decline in the
number of AIDS deaths during the
first quarter of 1996 comparted to
the same period in 1995.
While these combination thera
pies are proving effective, medical
researchers are apprehensive. Re
searchers speculate that the sup
pressed virus may exist only in
dormant, non-reproductive forms.
However, new findings show that
with certain stimuli, the dormant
virus can begin replicating again,
according to the Science magazine
article.
Based on this possibility, re
searchers say it is too early to con
sider taking patients off combina
tion therapy. Researchers must
assume that HTV infection is per
manent until there is conclusive
evidence to the contrary, accord
ing to the article.
In the meantime, combination
therapies are very effective in sup
pressing the virus, and patients are
reaping the benefits of keeping
their virus levels as low as possi
ble for as long as possible.
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Research shows that
combination therapies
have been effective in
lowering viral loads
By Ben Romano
Higher Education Reporter
Researchers have found that
drug “cocktails” can help sup
press the reproduction of HIV.
Combination drug therapies are
becoming more successful in sup
pressing the virus, according to a
March 1998 article in the Journal
of the American Medical Associa
tion. These combinations usually
consist of two or more drugs taken
on a strict regimen.
The combination therapies
have reduced the virus to unde
tectable levels in some cases. In
addition, patients taking combina
tion drugs have not shown signs of
developing a drug-resistant strain
of HIV, according to a November
1997 article in Science magazine.
A recent study conducted by
medical researchers from Italy, the
Netherlands, Canada and Aus
tralia concluded that certain drug
combinations can lead to sus