Nobel prize given to medical researchers
BOSTON (AP)— Two Swedes and an
Englishman shared the Nobel Prize for
Medicine on Monday for their research
into a group of body chemicals that
affect human ills ranging from arthritis
and high blood pressure to asthma and
painful menstruation
The prize was awarded to Sune Berg
strom and Bengt I Samuelsson of the
Karolinska Institute in Stockholm and
John R Vane of the Wellcome Research
Foundation in Beckenham, England,
who all happened to be in Boston at the
time
Their research has delved into the
workings and chemistry of a perplexing
group of substances called prostaglan
dins, which are similar to hormones
Scientists believe they may be able to
treat a variety of stubborn disorders by
manipulating these substances, found
throughout the human body and the
animal world.
All three men are in Boston this week
to speak at scientific meetings held as
part of the bicentennial celebration at
Harvard Medical School.
They sipped champagne together in a
medical school lecture hall, and Berg
strom promised they would hold "a joint
symposium" to figure out how to spend
the $157,000 prize money
"It’s certainly most gratifying that your
colleagues value the work that you have
been fighting with for the past 35 years,”
said Bergstrom, 66, who is sometimes
called the father of prostaglandin
chemistry
Added Samuelsson: "It's a very nice
way to wake up."
The three had shared the 1977 Albert
Lasker Basic Medical Award, given by
the Albert and Mary Lasker Foundaton in
New York, for their research
Prostaglandins were discovered in the
early 1930s, but only in the 1960s did
scientists learn how to make modified
versions, called analogues, that could be
used to treat specific disorders
The chemicals are now the subject of
intense study, and about 5,000 scientific
articles about them are published each
year
Among potential uses for the sub
stances are treating heart attacks, high
blood pressure, asthma, ulcers and
blocked nasal passages
Vane, 55, said many of the cardiovas
cular disorders that occur as people
grow older may soon be eased with
prostaglandins.
"The whole field has been one excite
ment after another,” he said
Vane's research into prostaglandins
revealed how aspirin works He dis
covered 11 years ago that the common
painkiller makes people feel better
because it blocks the body’s production
of prostaglandins
Prostaglandins are made in the body
from unsaturated fatty acids
"I think the coming 50 years will be just
as exciting as the past 50 have been in
this field,” said Bergstromm who also is
chairman of the board of directors of the
Nobel Foundation He and Samuelsson
began working together when Samuels
son was his student
Medicine was the first prize an
nounced this year in the series estab
lished in the will of Alfred Nobel, the
Swedish inventor of dynamite The next
award, the Peace Prize, will be an
nounced Wednesday by the Norwegian
Nobel Committee in Oslo.
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