Thur., June 21, 1962 The Newt-Review, Roieburg, Ore. 3
BYRD'S
CANNING, PRESERVING, FREEZING
Scientists Get
Look At Cancer
In Nature's Mice
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By DELOS SMITH
UPI Science Editor
NEW VOnif MlPil Pnr tho
first lime cancer research has
bad a very close look at what
Cancer Hups In nfltiirn'n nwn mirn
the mice housewives noiy havo
a chance to shriek at and which
may be living right now in your
cellar.
A larye amount, nf rancor rn.
search is done in mice but these
mice are science's animals rather
than naturnV ThnvVn hopn rhIpp.
lively bred, cross bred and inbred
over hundreds f mouse genera
tions, in ways that couldn't pos
sibly happen naturally.
In their hereditary chemistry
n.liltrn millrln't 1-npnnni.n onntA n
..... v .vu.t.Lb OUIHC VI
these lines as mice. Some linej
are pigmy susceptiblo to cancer.
Other lines are as highly resis
tant. TllA nilPStinn is hnur far ma
these mice from nature's own as
regards cancer?
Ors. Howard R Ami
Thelma B. Dunn of the National
Cancer Institute, Bethesda, Md.,
have been seeking the answer for
i years, iney now report that in
nature cancer and mice are well
acquainted, and apparently much
better acquainted than cancer and
people are.
Tho
list House Mice
scientists began
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. - " " -Khnu 111 jmi
with 19 freshly captured house
mice, la icmaies and 6 males, re
lationships (if any) unknown. In
1951 tnov SrlrlnH .in mnro nnUilun,
from live traps, equally divided
ueiween me sexes.
These mice and their progeny
then lived in cages for a sizeable
part of the mouse life snnn nr.
breeding and any intensive in.
breeding were prevented. Food,
water and cage-cleaning were pro
vided, of course. Otherwise sci
ence left them alone.
For a few years the mice which
remained in health were permit
ted to live for two years before,
they were subjected to a post
mortem search for cancer. In la
boratory mice that approximates
tho life span, but at two years
thn mipo wnrr flnuricliincr dill
Thereafter the mice were allowed
to live for two years and six
montns.
Drs. Andorvont and Dunn ' re
ported their autopsies of 225 mice
of which 98 had a malignant tu
mor or tumors. Thut's a nerppn.
tage of 43.5, much higher than
any of the various calculations or
incidence of cancer among human
beings.
Hits Older Mici
Of these mouse cancers, 64 per
cent appeared in mice who were
far past the prime of mouse life.
Only ono cancer appeared In a
quite young mouse and the re
maining tumors wore spread out
over mouse middle years. This
has agreement with cancer and
age in people.
Luna cancer was the most com
mon cancer among wild mice. It
was similar to lung cancer of In
bred laboratory mice in which it
also is common, but In the latter
it usually occurs in multiples
whereas In wild niico there was
only a single tumor.
In Inbred mice, lymphocytic
rjiulcfimin nlsn in common. "There
was only one case of it among
the wild mice, in inured mice it
may bo caused by a virus. Tho
scientists wondered if inbreeding
either increased the susceptibility
of mice to the virus or the ac
tivity of the virui or both.
This nupslinn thev couldn't an
swer at once, but another ques
tion they could and did answer.
Viruses which cnuso me leuKcmia
in inbred mice were injected into
wild mice and caused leukemia
in them, too.
HARD DAYS WORK
ST. LOUIS, Mo. (UPI) Tele-
vision news cameraman Jerry
Klciman went to film an exhibit
at tho Missiourl Historical Society
and onded up In tho hospital.
Klciman was filming . gun cot-
Inninr Jnhn Hoxtlorfer s demon
stration of an old muzzle loading
rifle when the weapon acciden
tally discharged, severing an ov
erhanging tree limb. A squirrel
which had been watcning tne pro
ceedings from the tree limb land
ed on Klciman and bit and
scratched him.
WHISTLE FIXER GONE
MENDOTA, 111. (UPI) - This
city is in the markot for a new
fire alarm whistle.
City fathers learned life last
person who knew how to repair
the old whistle no longer is a-round.
made naturally. ..